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HUANG Lei, WEI Shaozhong, CUI Diansheng, JIA Quan'an, LIU Sanhe, DENG Kangli. Clinical Effect of Laparoscopic Inguinal Lymph Node Dissection Versus Open Surgery for Penile Cancer[J]. Cancer Research on Prevention and Treatment, 2019, 46(4): 355-357. DOI: 10.3971/j.issn.1000-8578.2019.18.1285
Citation: HUANG Lei, WEI Shaozhong, CUI Diansheng, JIA Quan'an, LIU Sanhe, DENG Kangli. Clinical Effect of Laparoscopic Inguinal Lymph Node Dissection Versus Open Surgery for Penile Cancer[J]. Cancer Research on Prevention and Treatment, 2019, 46(4): 355-357. DOI: 10.3971/j.issn.1000-8578.2019.18.1285

Clinical Effect of Laparoscopic Inguinal Lymph Node Dissection Versus Open Surgery for Penile Cancer

More Information
  • Corresponding author:

    WEI Shaozhong, E-mail:weishaozhong@163.com

  • Received Date: September 06, 2018
  • Revised Date: November 14, 2018
  • Available Online: January 12, 2024
  • Objective 

    To compare the clinical effect of laparoscopic inguinal lymph node dissection versus open surgery for penile cancer, and to explore the feasibility of laparoscopic inguinal lymph node dissection.

    Methods 

    We retrospectively analyzed the data of 84 penile cancer patients who underwent inguinal lymph node dissection. Patients were divided into open group and laparoscopic group according to the surgical method of lymph node dissection. The preoperative data, intraoperative parameters, postoperative complications and efficacy of the two groups were analyzed.

    Results 

    There was no statistically significant difference in age, clinical tumor stage, lymph node size, the operative time, the number of lymph nodes dissected or intraoperative blood loss between the laparoscopic group and the open group (P > 0.05). But in terms of postoperative hospital stay, skin flap necrosis and postoperative incision infection rate, the incidence of postoperative lymphatic fistula, etc., there was statistical difference between the two groups (P < 0.05). Postoperative follow-up was 3 months to 2 years, in which 2 patients in the laparoscopic group recurred, while 3 patients in the open group relapsed, with no death and no statistically significant difference between the both groups (P > 0.05).

    Conclusion 

    Compared with open surgery, laparoscopic inguinal lymphadenectomy could obtain the same clinical curative effect, but with less trauma and postoperative complications.

  • [1]
    Chipollini J, Necchi A, Spiess PE. Outcomes for Patients with Node-positive Penile Cancer: Impact of Perioperative Systemic Therapies and the Importance of Surgical Intervention[J]. Eur Urol, 2018, 74(2): 241-2. doi: 10.1016/j.eururo.2018.04.025
    [2]
    Baiocchi G, Cestari FM, Rocha RM, et al. Does the count after inguinofemoral lymphadenectomy in vulvar cancer correlate with outcome?[J]. Eur J Surg Oncol, 2013, 39(4): 339-43. doi: 10.1016/j.ejso.2013.02.012
    [3]
    Micheletti L, Bogliatto F, Massobrio M. Groin lymphadenectomy with preservation of femoral fascia: total inguinofemoral node dissection for treatment of vulvar carcinoma[J]. World J Surg, 2005, 29(10): 1268-76. doi: 10.1007/s00268-005-7745-9
    [4]
    Colberg C, van der Horst C, Jünemann KP, et al. Epidemiology of penile cancer[J]. Urologe A, 2018, 57(4): 408-12. doi: 10.1007/s00120-018-0593-7
    [5]
    Júnior PFM, Silva EHV, Moura KL, et al. Increased Risk of Penile Cancer among Men Working in Agriculture[J]. Asian Pac J Cancer Prev, 2018, 19(1): 237-41. http://europepmc.org/articles/PMC5844624
    [6]
    Elsamra SE, Poch MA. Robotic inguinal lymphadenectomy for penile cancer: the why, how, and what[J]. Transl Androl Urol, 2017, 6(5): 826-32. doi: 10.21037/tau
    [7]
    Chipollini J, Tang DH, Manimala N, et al. Evaluating the accuracy of intraoperative frozen section during inguinal lymph node dissection in penile cancer[J]. Urol Oncol, 2018, 36(1): 14.e1-14.e5. http://europepmc.org/abstract/MED/29032883
    [8]
    Singh A, Jaipuria J, Goel A, et al. Comparing Outcomes of Robotic and Open Inguinal Lymph Node Dissection in Patients with Carcinoma of the Penis[J]. J Urol, 2018, 199(6): 1518-25. doi: 10.1016/j.juro.2017.12.061
    [9]
    Ornellas AA, Kinchin EW, Nóbrega BL, et al. Surgical treatment of invasive squamous cell carcinoma of the penis:Brazilian National Cancer Institute long-term experience[J]. J Surg Oncol, 2008, 97(6): 487-95. doi: 10.1002/(ISSN)1096-9098
    [10]
    Leone A, Diorio GJ, Pettaway C, et al. Contemporary management of patients with penile cancer and lymph node metastasis[J]. Nat Rev Urol, 2017, 14(6): 335-47. doi: 10.1038/nrurol.2017.47
    [11]
    Tsaur I, Biegel C, Gust K, et al. Feasibility, complications and oncologic results of a limited inguinal lymph node dissection in the management of penile cancer[J]. Int Braz J Urol, 2015, 41(3): 486-95. doi: 10.1590/S1677-5538.IBJU.2014.0304
    [12]
    Sotelo R, Sánchez-Salas R, Carmona O, et al. Endoscopic lymphadenectomy for penile carcinoma[J]. J Endourol, 2007, 21(4): 364-7. doi: 10.1089/end.2007.9971
    [13]
    Tobias-Machado M, Tavares A, Silva MN, et al. Can video endoscopic inguinal lymphadenectomy achieve a lower morbidity than open lymph node dissection in penile cancer patients?[J]. J Endourol, 2008, 22(8): 1687-91. doi: 10.1089/end.2007.0386
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