Advanced Search
HUANG Lei, WEI Shaozhong, CUI Diansheng, JIA Quan'an, LIU Sanhe, DENG Kangli. Clinical Effect of Laparoscopic Inguinal Lymph Node Dissection Versus Open Surgery for Penile Cancer[J]. Cancer Research on Prevention and Treatment, 2019, 46(4): 355-357. DOI: 10.3971/j.issn.1000-8578.2019.18.1285
Citation: HUANG Lei, WEI Shaozhong, CUI Diansheng, JIA Quan'an, LIU Sanhe, DENG Kangli. Clinical Effect of Laparoscopic Inguinal Lymph Node Dissection Versus Open Surgery for Penile Cancer[J]. Cancer Research on Prevention and Treatment, 2019, 46(4): 355-357. DOI: 10.3971/j.issn.1000-8578.2019.18.1285

Clinical Effect of Laparoscopic Inguinal Lymph Node Dissection Versus Open Surgery for Penile Cancer

More Information
  • Corresponding author:

    WEI Shaozhong, E-mail:weishaozhong@163.com

  • Received Date: September 06, 2018
  • Revised Date: November 14, 2018
  • Available Online: January 12, 2024
  • Objective 

    To compare the clinical effect of laparoscopic inguinal lymph node dissection versus open surgery for penile cancer, and to explore the feasibility of laparoscopic inguinal lymph node dissection.

    Methods 

    We retrospectively analyzed the data of 84 penile cancer patients who underwent inguinal lymph node dissection. Patients were divided into open group and laparoscopic group according to the surgical method of lymph node dissection. The preoperative data, intraoperative parameters, postoperative complications and efficacy of the two groups were analyzed.

    Results 

    There was no statistically significant difference in age, clinical tumor stage, lymph node size, the operative time, the number of lymph nodes dissected or intraoperative blood loss between the laparoscopic group and the open group (P > 0.05). But in terms of postoperative hospital stay, skin flap necrosis and postoperative incision infection rate, the incidence of postoperative lymphatic fistula, etc., there was statistical difference between the two groups (P < 0.05). Postoperative follow-up was 3 months to 2 years, in which 2 patients in the laparoscopic group recurred, while 3 patients in the open group relapsed, with no death and no statistically significant difference between the both groups (P > 0.05).

    Conclusion 

    Compared with open surgery, laparoscopic inguinal lymphadenectomy could obtain the same clinical curative effect, but with less trauma and postoperative complications.

  • [1]
    Chipollini J, Necchi A, Spiess PE. Outcomes for Patients with Node-positive Penile Cancer: Impact of Perioperative Systemic Therapies and the Importance of Surgical Intervention[J]. Eur Urol, 2018, 74(2): 241-2. doi: 10.1016/j.eururo.2018.04.025
    [2]
    Baiocchi G, Cestari FM, Rocha RM, et al. Does the count after inguinofemoral lymphadenectomy in vulvar cancer correlate with outcome?[J]. Eur J Surg Oncol, 2013, 39(4): 339-43. doi: 10.1016/j.ejso.2013.02.012
    [3]
    Micheletti L, Bogliatto F, Massobrio M. Groin lymphadenectomy with preservation of femoral fascia: total inguinofemoral node dissection for treatment of vulvar carcinoma[J]. World J Surg, 2005, 29(10): 1268-76. doi: 10.1007/s00268-005-7745-9
    [4]
    Colberg C, van der Horst C, Jünemann KP, et al. Epidemiology of penile cancer[J]. Urologe A, 2018, 57(4): 408-12. doi: 10.1007/s00120-018-0593-7
    [5]
    Júnior PFM, Silva EHV, Moura KL, et al. Increased Risk of Penile Cancer among Men Working in Agriculture[J]. Asian Pac J Cancer Prev, 2018, 19(1): 237-41. http://europepmc.org/articles/PMC5844624
    [6]
    Elsamra SE, Poch MA. Robotic inguinal lymphadenectomy for penile cancer: the why, how, and what[J]. Transl Androl Urol, 2017, 6(5): 826-32. doi: 10.21037/tau
    [7]
    Chipollini J, Tang DH, Manimala N, et al. Evaluating the accuracy of intraoperative frozen section during inguinal lymph node dissection in penile cancer[J]. Urol Oncol, 2018, 36(1): 14.e1-14.e5. http://europepmc.org/abstract/MED/29032883
    [8]
    Singh A, Jaipuria J, Goel A, et al. Comparing Outcomes of Robotic and Open Inguinal Lymph Node Dissection in Patients with Carcinoma of the Penis[J]. J Urol, 2018, 199(6): 1518-25. doi: 10.1016/j.juro.2017.12.061
    [9]
    Ornellas AA, Kinchin EW, Nóbrega BL, et al. Surgical treatment of invasive squamous cell carcinoma of the penis:Brazilian National Cancer Institute long-term experience[J]. J Surg Oncol, 2008, 97(6): 487-95. doi: 10.1002/(ISSN)1096-9098
    [10]
    Leone A, Diorio GJ, Pettaway C, et al. Contemporary management of patients with penile cancer and lymph node metastasis[J]. Nat Rev Urol, 2017, 14(6): 335-47. doi: 10.1038/nrurol.2017.47
    [11]
    Tsaur I, Biegel C, Gust K, et al. Feasibility, complications and oncologic results of a limited inguinal lymph node dissection in the management of penile cancer[J]. Int Braz J Urol, 2015, 41(3): 486-95. doi: 10.1590/S1677-5538.IBJU.2014.0304
    [12]
    Sotelo R, Sánchez-Salas R, Carmona O, et al. Endoscopic lymphadenectomy for penile carcinoma[J]. J Endourol, 2007, 21(4): 364-7. doi: 10.1089/end.2007.9971
    [13]
    Tobias-Machado M, Tavares A, Silva MN, et al. Can video endoscopic inguinal lymphadenectomy achieve a lower morbidity than open lymph node dissection in penile cancer patients?[J]. J Endourol, 2008, 22(8): 1687-91. doi: 10.1089/end.2007.0386
  • Related Articles

    [1]DAI Nan, ZHAO Xiaolong, DAI Xiaoyan, LI Mengxia. Effect of Exosomal APE1 on Sensitivity of NSCLC A549 Cells to Cisplatin[J]. Cancer Research on Prevention and Treatment, 2020, 47(7): 492-497. DOI: 10.3971/j.issn.1000-8578.2020.19.1609
    [2]HUANG Zejian, FANG Chang, YU Baodan, CHENG Qing, LYU Ping. 3E10 Targeting CD24 Enhances Chemotherapy Sensitivity of Hepatocellular Carcinoma HuH-7 Cells[J]. Cancer Research on Prevention and Treatment, 2018, 45(8): 540-544. DOI: 10.3971/j.issn.1000-8578.2018.17.1484
    [3]CAI Rui, CHEN Qiuqiu, JIANG Wei. 5-azacytidine Increases Radiation Sensitivity of Nasopharyngeal Carcinoma Cell Line C666-1[J]. Cancer Research on Prevention and Treatment, 2017, 44(2): 94-97. DOI: 10.3971/j.issn.1000-8578.2017.02.003
    [4]ZHANG Juping, SHI Yehui, JIA Yongsheng, ZHOU Liyan, TONG Zhongsheng. GDF11 is Involved in Human Hepatic Carcinoma Cells SMMC-7721 Proliferation and Sensitivity to DDP[J]. Cancer Research on Prevention and Treatment, 2016, 43(6): 459-462. DOI: 10.3971/j.issn.1000-8578.2016.06.005
    [5]LI Wei, PENG Junqin, LI Jiansheng, TANG Rijie. MR Apparent Diffusion Coefficient Predicts Sensitivity of Nasopharyngeal Carcinoma to Radiotherapy and Related Factors[J]. Cancer Research on Prevention and Treatment, 2015, 42(12): 1221-1226. DOI: 10.3971/j.issn.1000-8578.2015.12.011
    [6]HU Lili, YIN Yanjun, ZHONG Wenjuan, QIU Feng. miR-200c Enhances Sensitivity of Lung Cancer Cell A549 to Paclitaxel and Gefitinib and Related Mechanism[J]. Cancer Research on Prevention and Treatment, 2015, 42(08): 760-764. DOI: 10.3971/j.issn.1000-8578.2015.08.003
    [7]CAO Xinmei, ZHANG Daiquan, XIA Jiyi, WANG Xu, GAO Yan, XIONG Wei. Effects of HER2 shRNA on Chemotherapy Sensitivity of Mouse Lewis Cells[J]. Cancer Research on Prevention and Treatment, 2014, 41(05): 366-368. DOI: 10.3971/j.issn.1000-8578.2014.05.004
    [8]Yang Qingshan, Liu Yuanyuan, Jiang Lipeng. Effect of Expression Vector of Human BAG-1 Gene on Radio-sensitivity of Lung Adenocarcinoma Cells[J]. Cancer Research on Prevention and Treatment, 2012, 39(02): 127-129. DOI: 10.3971/j.issn.1000-8578.2012.02.002
    [9]FANG Chuan, TAN Yan-li, WANG Jia-liang, SHI Yan-fang, SHAN Xiao-song, LI Wei. Primary Culture and Drug Sensitivity of Human Glioma Cells[J]. Cancer Research on Prevention and Treatment, 2010, 37(12): 1380-1382. DOI: 10.3971/j.issn.1000-8578.2010.12.012
    [10]ZHANG Wei, GU Min. Geldanamycin Sensitizes Human Breast Cancer Cells to Adriamycin both in vitro and in vivo[J]. Cancer Research on Prevention and Treatment, 2010, 37(10): 1109-1112. DOI: 10.3971/j.issn.1000-8578.2010.10.004
  • Cited by

    Periodical cited type(9)

    1. 成俊,徐雪峰,李伟. D-CBCT在肺癌容积旋转调强计划精准治疗中的临床应用. 中国CT和MRI杂志. 2024(04): 35-37 .
    2. 蒋浩,曹新超,吴桐,郭志斌. 低剂量CT联合外周血循环肿瘤细胞在肺癌早期诊断中的价值研究. 中国CT和MRI杂志. 2024(06): 57-60 .
    3. 王晶,翟成凯. 肿瘤自身抗体及CT人工智能在NSCLC早期诊断中的应用研究进展. 解放军医学杂志. 2024(07): 848-854 .
    4. 李雪娇. 多排螺旋CT低剂量胸部扫描在肺癌早期筛查中的应用价值分析. 医药前沿. 2024(15): 79-81 .
    5. 易梅玲,易芳玲. 双层探测器光谱CT智能剂量调控技术在低剂量胸部体检中的应用价值. 中国医疗器械信息. 2024(22): 8-10+81 .
    6. 杏子,彭源. 低剂量CT在肺癌筛查中的价值. 中国防痨杂志. 2024(S2): 234-236 .
    7. 陈蔚,蒋伟. 低剂量螺旋CT扫描用于肺癌筛查及鉴别的效果评估. 深圳中西医结合杂志. 2023(01): 71-73 .
    8. 慕珂珂,肖凌云,董炎红. 早期肺癌患者血清和胸腔积液中CYFRA211、NSE及SCC水平变化及意义. 中国实用医刊. 2023(09): 34-37 .
    9. 陈彪. 低剂量螺旋CT联合血清肿瘤标志物在肺癌诊断中的临床应用价值. 影像研究与医学应用. 2023(22): 24-26 .

    Other cited types(1)

Catalog

    Article views (1418) PDF downloads (654) Cited by(10)

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return