| Citation: |
LIU Fengqiong, YAN Lingjun, CHEN Fa, HUANG Jiangfeng, LIU Fangping, QIU Yu, LIN Lisong, ZHENG Xiaoyan, WU Junfeng, HE Baochang. Association Between Tea Consumption and Risk of Gingival Carcinoma: A Case-control Study[J]. Cancer Research on Prevention and Treatment, 2017, 44(2): 138-141. DOI: 10.3971/j.issn.1000-8578.2017.02.012
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To assess the effect of tea consumption on incidence of gingival carcinoma.
A case-control study including 121 gingival carcinoma patients confirmed by pathological diagnoses and 363 gender-age frequency matched controls were enrolled in Fujian province from December 2010 to March 2016. Unconditional logistic regression was used to calculate adjusted odds ratios (ORs) and corresponding 95% confidence intervals (CIs) to assess the effects of tea related variables on gingival carcinoma and interaction analysis.
Tea consumption was associated with decreased risk of gingival carcinoma(OR=0.51, 95%CI: 0.29-0.75). Moreover, with a greater daily quantity and a longer duration of tea-drinking, the risk of gingival carcinoma was reduced (all Ptrend<0.05). Furtherly, age of tea drinking initiation (years) more than 25, moderate concentration as well as temperature of tea, drinking green tea and oolong tea were also showed decreased the risk of gingival carcinoma. The stratificated analysis indicated that the protective effect of tea drinking was more evident among non-tobacco smokers(OR=0.40, 95%CI: 0.17-0.96), but no significance was observed in the alcohol drinkers or non-alcohol drinkers. No significantly multiplicative interaction was observed between smoking and tea. The same re sult was found between alcohol drinking and tea.
Tea consumption plays a protective effect on gingival carcinoma. Moreover, there is dose-response relationship between daily quantity or duration of tea-drinking and risk of gingival cancer.
| [1] |
傅锦业, 高静, 郑家伟, 等. 我国东南地区口腔黏膜鳞癌发病状况的描述性分析[J]. 中国口腔颌面外科, 2014, 12(3): 261-5. http://www.cnki.com.cn/Article/CJFDTOTAL-ZGKQ201403024.htm
Fu JY, Gao J, Zheng JW, et al. Descriptive analysis of oral squamous cell cancer incidence in south and east China[J]. Zhongguo Kou Qiang He Mian Wai Ke, 2014, 12(3): 261-5. http://www.cnki.com.cn/Article/CJFDTOTAL-ZGKQ201403024.htm
|
| [2] |
郭朱明, 王顺兰, 张诠, 等. 116例牙龈癌的治疗与预后分析[J]. 癌症, 2008, 27(3): 307-10. http://www.cnki.com.cn/Article/CJFDTOTAL-AIZH200803017.htm
Guo ZM, Wang SL, Zhang Q, et al. Treatment and Prognosis of Gingival Carcinoma: A Report of 116 Cases[J]. Ai Zheng, 2008, 27(3): 307-10. http://www.cnki.com.cn/Article/CJFDTOTAL-AIZH200803017.htm
|
| [3] |
Rao DN, Desai PB. Risk assessment of tobacco, alcohol and diet in cancers of base tongue and oral tongue-a case control study[J]. Indian J Cancer, 1998, 35(2): 65-72. https://www.ncbi.nlm.nih.gov/pubmed/9849026
|
| [4] |
Mohan KV, Gunasekaran P, Varalakshmi E, et al. In vitro evaluation of the anticancer effect of lactoferrin and tea polyphenol combination on oral carcinoma cells[J]. Cell Biol Int, 2007, 31(6): 599-608. doi: 10.1016/j.cellbi.2006.11.034
|
| [5] |
Sur S, Pal D, Roy R, et al. Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice[J]. Toxicol Appl Pharmacol, 2016, 300: 34-46. doi: 10.1016/j.taap.2016.03.016
|
| [6] |
陈法, 蔡琳, 何保昌, 等. 饮茶与非吸烟, 非饮酒人群口腔癌的关系研究[J]. 中华预防医学杂志, 2015, 49(8): 683-7.
Chan F, Cai L, He BC, et al. Effect of tea on oral cancer in nonsmokers and nondrinkers: a case-control study[J]. Zhonghua Yu Fang Yi Xue Za Zhi, 2015, 49(8): 683-7.
|
| [7] |
杨功焕, 马杰民, 刘娜, 等. 中国人群2002年吸烟和被动吸烟的现状调查[J]. 中华流行病学杂志, 2005, 26(2): 77-83. http://www.cnki.com.cn/Article/CJFDTOTAL-ZHLX200502000.htm
Yang GH, Ma JM, Liu N, et al. Smoking and passive smoking in Chinese, 2002[J]. Zhonghua Liu Xing Bing Xue Za Zhi, 2005, 26(2): 77-83. http://www.cnki.com.cn/Article/CJFDTOTAL-ZHLX200502000.htm
|
| [8] |
张林峰, 赵连成, 周北凡, 等. 男性饮酒与缺血性脑卒中发病关系的研究[J]. 中华流行病学杂志, 2004, 25(11): 945-57. http://www.cnki.com.cn/Article/CJFDTOTAL-ZHLX200411011.htm
Zhang LF, Zhao LC, Zhou BF, et al. Alcohol consumption and incidence of ischemic stroke in male Chinese[J]. Zhonghua Liu Xing Bing Xue Za Zhi, 2004, 25(11): 945-57. http://www.cnki.com.cn/Article/CJFDTOTAL-ZHLX200411011.htm
|
| [9] |
Chen F, He B, Hu Z, et al. Passive smoking and cooking oil fumes (COF) may modify the association between tea consumption and oral cancer in Chinese women[J]. J Cancer Res Clin Oncol, 2016, 142(5): 995-1001. doi: 10.1007/s00432-016-2123-6
|
| [10] |
江穗, 陈锡林, 丁咏, 等. 没食子儿茶素没食子酸酯诱导人口腔上皮癌细胞G1期阻滞[J]. 南方医科大学学报, 2009, 29(7): 1381-3. http://www.cnki.com.cn/Article/CJFDTOTAL-DYJD200907021.htm
Jiang H, Chen XL, Ding Y, et al. Epigallocatechin-3-gallate induces G1 phase cell cycle arrest in KB cells[J]. Nan Fang Yi Ke Da Xue Xue Bao, 2009, 29(7): 1381-3. http://www.cnki.com.cn/Article/CJFDTOTAL-DYJD200907021.htm
|
| [11] |
Fujiki H, Sueoka E, Watanabe T, et al. Primary cancer prevention by green tea, and tertiary cancer prevention by the combination of green tea catechins and anticancer compounds[J]. J Cancer Prev, 2015, 20(1): 1-4. doi: 10.15430/JCP.2015.20.1.1
|
| [12] |
Radoï L, Paget-Bailly S, Menvielle G, et al. Tea and coffee consumption and risk of oral cavity cancer: results of a large population-based case-control study, the ICARE study[J]. Cancer Epidemiol, 2013, 37(3): 284-9. doi: 10.1016/j.canep.2013.02.001
|
| [13] |
Ide R, Fujino Y, Hoshiyama Y, et al. A prospective study of green tea consumption and oral cancer incidence in Japan[J]. Ann Epidemiol, 2007, 17(10): 821-6. doi: 10.1016/j.annepidem.2007.04.003
|
| [14] |
Zhao X, Pang L, Li J, et al. Apoptosis inducing effects of Kuding tea polyphenols in human buccal squamous cell carcinoma cell line BcaCD885[J]. Nutrients, 2014, 6(8): 3084-100. doi: 10.3390/nu6083084
|
| [15] |
刘晓亮, 刘环秋, 李季, 等. 绿茶提取物对口腔鳞癌抗肿瘤效应及作用机制的研究[J]. 中国中西医结合杂志, 2014, 34(11): 1369-73. http://www.cnki.com.cn/Article/CJFDTOTAL-ZZXJ201411021.htm
Liu XL, Liu HQ, Li J, et al. Experimental study on anti-tumor effect and mechanism of green tea extract[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 2014, 34(11): 1369-73. http://www.cnki.com.cn/Article/CJFDTOTAL-ZZXJ201411021.htm
|
| [16] |
Islami F, Pourshams A, Nasrollahzadeh D, et al. Tea drinking habits and oesophageal cancer in a high risk area in northern Iran: population based case-control study[J]. BMJ, 2009, 338(2): b929.
|
| [17] |
Whiteman DC. Hot tea and increased risk of oesophageal cancer[J]. BMJ, 2009, 338: b610. doi: 10.1136/bmj.b610
|
| [18] |
Chen Z, Chen Q, Xia H, et al. Green tea drinking habits and esophageal cancer in southern China: a case-control study[J]. Asian Pac J Cancer Prev, 2011, 12(1): 229-33.
|
| [19] |
Mirvish SS. Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC[J]. Cancer Lett, 1995, 93(1): 17-48. doi: 10.1016/0304-3835(95)03786-V
|
| [20] |
Li ZG, Shimada Y, Sato F, et al. Promotion effects of hot water on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in F344 rats[J]. Oncol Rep, 2003, 10(2): 421-6.
|
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