Prognostic Factors for Extragastrointestinal Stromal Tumors Patients

GAO Yebo; HUA Baojin; FU Qiang; XIE Jianguo

doi:10.3971/j.issn.1000-8578.2014.012.015

Cancer Research on Prevention and Treatment > 2014 > 41(12): 1322-1325. > DOI: 10.3971/j.issn.1000-8578.2014.012.015

GAO Yebo, HUA Baojin, FU Qiang, XIE Jianguo. Prognostic Factors for Extragastrointestinal Stromal Tumors Patients[J]. Cancer Research on Prevention and Treatment, 2014, 41(12): 1322-1325. DOI: 10.3971/j.issn.1000-8578.2014.012.015

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Prognostic Factors for Extragastrointestinal Stromal Tumors Patients

GAO Yebo^1,2,
HUA Baojin^1, ,,
FU Qiang³,
XIE Jianguo^3, ,

1.Department of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China; 2.Clinical Medical College, Beijing University of Traditional Chinese Medicine, Beijing 100029, China; 3.Department of General Surgery, The Tumor Hospital, Affiliated to Zhengzhou University, He,nan Tumor Hospital, Zhengzhou 450008, China

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Received Date: March 16, 2014
Revised Date: May 11, 2014

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Abstract

Abstract

Objective To explore clinical features and prognostic factors of extragastrointestinal stromal tumors(EGSTs). Methods We retrospectively analyzed clinicopathological data of 35 EGSTs patients admitted from January 2006 to May 2011 in Henan Tumor Hospital by SPSS17.0. Kaplan-Meier and Cox regression(forward stepwise regression) analysis were used to evaluate the prognostic factors(P<0.05). Results 1-, 2- and 3-year survival rates of all EGST patients were 81.6%, 57.3% and 35.3%; 18 patients (51.4%) with R0 resection developed recurrence or metastasis. Cox regression analysis showed that the surrounding tissue invasion (RR: 3.386, 95% CI: 1.142-10.044), tumor recurrence or metastasis (RR: 2.269, 95% CI: 1.055-4.880), tumor hemorrhage necrosis (RR: 3.015,95%CI: 1.120-4.880) and tumor rupture (RR: 8.085,95%CI: 2.517-25.967) were independent prognostic factors. Conclusion EGIST symptoms are dormant and difficult to diagnose, with large volume at first. Surrounding tissue invasion, tumor recurrence or metastasis, tumor hemorrhage necrosis and rupture are independent prognostic factors.
- Extragastrointestinal stromal tumors(EGSTs),
- Clinical features,
- Prognosis factors

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References

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