Evaluation of radiotherapy plus chemotherapy in the treatment of patients with stace Ⅲ adenocarcinoma of lung

Between 1989 and 1992, 52 patients with stage Ⅲ adenocarcinoma of lung were treated, of them, 24_underwent radiotherapy only and 28 were treated by radiotherapy plus chemotherapy. The response rate (CR+PR) were 33.35 and 53.6% respectively (P>0.1). In patients with chemotherapy, the incidence of side effects (vomiting, nausea, Ieucopenia and thrombocytopenia) was significantly higher than those without chemotherapy (P<0.05). but no discontinuation of the treatment happened because of side effects. In patients without chemotherapy, the systemic metastase rate was higher than patients with chemotherapy (33%:18%). but no statistical differance was found. It was suggested that radiotherapy plus chemotherapy in the treatment of patients with stage Ⅲ adenocarcinoma of lung did not show better result.