Pathology Study about Osteosarcoma Invaded Epiphyseal Plate and Cartilage and MVD,the Expression of VEGF.SMA.Desmin and Their Relationship

Objective To explore the role of epiphyseal plate and cartilage whether or not to resist the invasion of osteosarcoma(OS).tumor stage of invasion.mode of invasion and mechanism of genesis. Methods Use the OS specimen of 57 cases of amputation,saw these specimen into spicula of 1cm thick in vertical direction,and make X-ray photograph of multi-spicula,Draw materials in various plane of epiphyseal plate and cartilage, observe the invasive condition of OS to epiphyseal plate and cartilage under light microscope...