Treatment of Advanced Primary Hepatocellular Carcinoma with low dose of and FM or FAM

Forty patients with primary hepatocellular carcinoma were treated with low does CF(LDCF) andFM or FAM Chemotherapy regimens, the does Of CF is 20mg/m²/d for 5 days, other chemotherapeuticdrugs are usual doeses and usage. Each patient was treated two or over two courses. The results showedthat the therapeutic effective rate was 30%(12/40), 8 cases survived more than 12 months; amongthem, 1 survived more than 34 months and another survived more than 46 months. It suggested thatLDCF plus FM or FAM has a clinic significance for treatment of advanced hepatocellular carcinoma andmay be try to prevent extraheptic metastasis.