Surgical Treatment of Colorectal Cancer Patients with Ileus Aged Over 80 Years

Objective To investigate the surgical treatment strategy for colorectal cancer patients with ileus aged over 80 years old.

Methods We retrospectively collected and analyzed the clinicopathological data of patients with preoperative ileus aged over 80 years old who underwent colorectal cancer surgery from January 2007 to December 2018. According to the surgical method, the patients were divided into the radical surgery group (n=58) and the non-radical surgery group (n=19). The clinicopathological characteristics, perioperative indicators and prognosis of the two groups were compared. Kaplan-Meier method was used for survival analysis and Cox regression analysis was conducted to analyze prognostic factors.

Results A total of 77 patients were included. The proportion of patients with stage Ⅳ in the radical treatment group was significantly lower than that in the non-radical treatment group (P < 0.001). The 5-year survival rate of the radical surgery group was significantly higher than that of the non-radical surgery group (P < 0.001). Univariate analysis showed that the predictors for survival were TNM stage and radical surgery. Multivariate analysis showed that radical surgery was an independent factor affecting the prognosis of colorectal cancer patients with ileus aged over 80 years old.

Conclusion Radical surgery is an independent factor affecting the prognosis of colorectal cancer patients with ileus aged over 80 years old.