Advanced Search
PEI Wei, ZHOU Sicheng, LIANG Jianwei, ZHOU Haitao, LIU Qian, ZHOU Zhixiang, WANG Xishan. Surgical Treatment of Colorectal Cancer Patients with Ileus Aged Over 80 Years[J]. Cancer Research on Prevention and Treatment, 2020, 47(6): 466-470. DOI: 10.3971/j.issn.1000-8578.2020.19.1376
Citation: PEI Wei, ZHOU Sicheng, LIANG Jianwei, ZHOU Haitao, LIU Qian, ZHOU Zhixiang, WANG Xishan. Surgical Treatment of Colorectal Cancer Patients with Ileus Aged Over 80 Years[J]. Cancer Research on Prevention and Treatment, 2020, 47(6): 466-470. DOI: 10.3971/j.issn.1000-8578.2020.19.1376

Surgical Treatment of Colorectal Cancer Patients with Ileus Aged Over 80 Years

More Information
  • Corresponding author:

    LIANG Jianwei, E-mail: liangjw1976@126.com

  • Received Date: November 03, 2019
  • Revised Date: March 11, 2020
  • Available Online: January 12, 2024
  • Objective 

    To investigate the surgical treatment strategy for colorectal cancer patients with ileus aged over 80 years old.

    Methods 

    We retrospectively collected and analyzed the clinicopathological data of patients with preoperative ileus aged over 80 years old who underwent colorectal cancer surgery from January 2007 to December 2018. According to the surgical method, the patients were divided into the radical surgery group (n=58) and the non-radical surgery group (n=19). The clinicopathological characteristics, perioperative indicators and prognosis of the two groups were compared. Kaplan-Meier method was used for survival analysis and Cox regression analysis was conducted to analyze prognostic factors.

    Results 

    A total of 77 patients were included. The proportion of patients with stage Ⅳ in the radical treatment group was significantly lower than that in the non-radical treatment group (P < 0.001). The 5-year survival rate of the radical surgery group was significantly higher than that of the non-radical surgery group (P < 0.001). Univariate analysis showed that the predictors for survival were TNM stage and radical surgery. Multivariate analysis showed that radical surgery was an independent factor affecting the prognosis of colorectal cancer patients with ileus aged over 80 years old.

    Conclusion 

    Radical surgery is an independent factor affecting the prognosis of colorectal cancer patients with ileus aged over 80 years old.

  • [1]
    陈万青, 张思维, 曾红梅, 等.中国2010年恶性肿瘤发病与死亡[J].中国肿瘤, 2014, 23(1): 1-10. http://d.old.wanfangdata.com.cn/Periodical/zgzl201401001

    Chen WQ, Zhang SW, Zeng HM, et al. Report of Cancer Incidence and Mortality in China, 2010[J]. Zhongguo Zhong Liu, 2014, 23(1): 1-10. http://d.old.wanfangdata.com.cn/Periodical/zgzl201401001
    [2]
    Clavien PA, Barkun J, de Oliveira ML, et al. The Clavien-Dindo classification of surgical complications: five-year experience[J]. Ann Surg, 2009, 250(2): 187-196. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=10.1097/DCR.0000000000001679
    [3]
    Rasool S, Kadla SA, Rasool V, et al. A comparative overview of general risk factors associated with the incidence of colorectal cancer[J]. Tumour Biol, 2013, 34(5): 2469-2476. http://cn.bing.com/academic/profile?id=01b60676d3107ef08bd3da91506f2038&encoded=0&v=paper_preview&mkt=zh-cn
    [4]
    Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012[J]. Int J Cancer, 2015, 136(5): E359-E386. http://cn.bing.com/academic/profile?id=92998753a0e7f31e127db34e72d37cd5&encoded=0&v=paper_preview&mkt=zh-cn
    [5]
    van Eeghen EE, den Boer FC, Loffeld RJ. Thirty days post-operative mortality after surgery for colorectal cancer: a descriptive study[J]. J Gastrointest Oncol, 2015, 6(6): 613-617. http://pubmedcentralcanada.ca/pmcc/articles/PMC4671843/
    [6]
    Tanis PJ, Paulino Pereira NR, van Hooft JE, et al. Resection of obstructive left-sided colon cancer at a national level: A prospective analysis of short-term outcomes in 1816 patients[J]. Dig Surg, 2015, 32(5): 317-324. https://www.narcis.nl/publication/RecordID/oai%3Apure.amc.nl%3Apublications%2Fb98a4fcf-f132-4a5e-a7da-1cf2be7121d3
    [7]
    Dekker JW, Gooiker GA, Bastiaannet E, et al. Cause of death the first year after curative colorectal cancer surgery; a prolonged impact of the surgery in elderly colorectal cancer patients[J]. Eur J Surg Oncol, 2014, 40(11): 1481-1487. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=6f5fde3c531c40133f6c97cd62663c87
    [8]
    Takeuchi K, Tsuzuki Y, Audo T, et al. Should patients over 85 years old be operated on for colorectal cancer?[J]. J Clin Gastroenrol, 2004, 38(5): 408-413. http://cn.bing.com/academic/profile?id=07b625991b96439c27158814937740e0&encoded=0&v=paper_preview&mkt=zh-cn
    [9]
    Bruce C, Köhne CH, Audisio RA. Treatment of advanced colorectal cancer in the elderly[J]. Eur J Surg Oncol, 2007, 33(Suppl 2): S84-S87. http://d.old.wanfangdata.com.cn/OAPaper/oai_pubmedcentral.nih.gov_2361238
    [10]
    周晓刚, 王林, 覃先蓬, 等.腹腔镜与肠梗阻导管联合治疗老年梗阻性结直肠癌临床观察[J].现代肿瘤医学, 2019, 27(6): 998-1001. http://d.old.wanfangdata.com.cn/Periodical/sxzlyx201906023

    Zhou XG, Wang L, Qin XP, et al. Clinical observation of laparoscopy combined with intestinal obstruction catheter in treating elderly patients with obstructive colorectal cancer[J].Xian Dai Zhong Liu Yi Xue, 2019, 27(6): 998-1001. http://d.old.wanfangdata.com.cn/Periodical/sxzlyx201906023
    [11]
    黄成宽.腹腔镜结直肠癌手术在老年结直肠癌患者中的应用效果[J].中国肛肠病杂志, 2019, 39(8): 8-9. http://d.old.wanfangdata.com.cn/Periodical/zggcbzz201908004

    Huang CK. Application Effect of Laparoscopic Procedure for Colorectal Cancer of Senior Patients[J]. Zhongguo Gang Chang Bing Za Zhi, 2019, 39(8): 8-9. http://d.old.wanfangdata.com.cn/Periodical/zggcbzz201908004
    [12]
    周思成, 王征, 周海涛, 等.合并心血管疾病对80岁以上老年结直肠癌患者围手术期的影响分析[J].中国肿瘤临床, 2019, 46(5): 233-238. http://d.old.wanfangdata.com.cn/Periodical/zgzllc201905009

    Zhou SC, Wang Z, Zhou HT, et al. Effect of cardiovascular comorbidities on the perioperative period of patients with colorectal cancer aged over 80 years[J]. Zhongguo Zhong Liu Lin Chuang, 2019, 46(5): 233-238. http://d.old.wanfangdata.com.cn/Periodical/zgzllc201905009
  • Related Articles

    [1]LI Ping, GUO Xu. Current Status of Off-label Use of Denosumab in Bone Tumor and Bone Diseases[J]. Cancer Research on Prevention and Treatment, 2023, 50(3): 316-320. DOI: 10.3971/j.issn.1000-8578.2023.22.0860
    [2]HAN Boqiang, MA Youwei, YU Jianping, LIU Hongbin, HAN Xiaopeng. Application of Nano-carbon Tracer in Da Vinci Robot-assisted Radical Thyroidectomy[J]. Cancer Research on Prevention and Treatment, 2020, 47(4): 288-293. DOI: 10.3971/j.issn.1000-8578.2020.19.1143
    [3]GUO Xiongbo, HUANG Bin, LIU Baohua, LI Chunxue, YE Jingwang, DENG Xiaolian. Application of Carbon Nanoparticles in Da Vinci Radical Resection of Rectal Carcinoma[J]. Cancer Research on Prevention and Treatment, 2018, 45(11): 905-908. DOI: 10.3971/j.issn.1000-8578.2018.18.0235
    [4]LIU Shan, DUAN Lincan, JIANG Yongxin. Application Advances of Carbon Nanoparticles in Therapy for Lung Carcinoma[J]. Cancer Research on Prevention and Treatment, 2015, 42(08): 848-851. DOI: 10.3971/j.issn.1000-8578.2015.08.021
    [5]Lv Liang, Zhang Yanbin, Zhuo Hongqing, Zhang Hui, Jiang Kewei, Ye Yingjiang, Wang Shan. Role of Quantitative Proteomic Strategy by Laser Capture Microdissection Combined with Acetylation Stable Isotope Labeling in Colorectal Cancer[J]. Cancer Research on Prevention and Treatment, 2012, 39(08): 923-926. DOI: 10.3971/j.issn.1000-8578.2012.08.010
    [6]LIU Hua-qing, HU-Li. Application of Combination of Double-labelling with Immunohistochemistry and Laser Capture Microdissection in Hodgkin's Lymphoma[J]. Cancer Research on Prevention and Treatment, 2010, 37(04): 438-440. DOI: 10.3971/j.issn.1000-8578.2010.04.019
    [7]XU Qing-Hua, SU Bo, ZHAO Yin-Min, TANG Liang, ZHOU Cai-Cun. Evaluation of Tumor Vascular Targeting Agents Labelled with 131 I in Imaging of Tumor[J]. Cancer Research on Prevention and Treatment, 2007, 34(11): 860-863. DOI: 10.3971/j.issn.1000-8578.498
    [8]ZHENG Lei, HAN Yue-wu. Antisense Oligodeoxyribonucleotide Target Ki-67 Inhibits Proliferation of Human Hepatocellucar Carcinoma Cell HEPG-7402 in Vitro[J]. Cancer Research on Prevention and Treatment, 2006, 33(12): 862-864. DOI: 10.3971/j.issn.1000-8578.354
    [9]WEI Ai-jun, ZHANG You-yuan, XIONG Mi, et al, . MCD/MVD were inspected with immunohistochemical double labeled and quantitative analysis in the gastric carcinoma and its significance[J]. Cancer Research on Prevention and Treatment, 2004, 31(01): 17-18. DOI: 10.3971/j.issn.1000-8578.2036

Catalog

    Article views (1796) PDF downloads (765) Cited by()

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return