Liver Cancer Incidence and Mortality Rates During Last 40 Years in Hebei Province

Objective To estimate the liver cancer burden and analyze the trend of the mortality rate during last 40 years in Hebei Province.

Methods Cancer registry data from nine cancer registries in Hebei Province were qualified and checked according to the regulations from the National Cancer Registry Center. The pooled data were stratified by gender and age. Incidence and mortality rates were calculated and expressed in 1/100 000. Liver cancer mortality data during the three periods were extracted and calculated from the national death surveys. Mortality and incidence trends in Ci County from 1988 to 2012 were analyzed by Joinpoint Regression Models.

Results The newly liver cancer cases and deaths from 2010 to 2012 in Hebei Province were 2 552 and 2 447,respectively. The crude incidence rate (CIR) of liver cancer was 18.26/100 000 (24.89/100 000 in male and 11.40/100 000 in female). The age-standardized incidence rate by world standard population (ASIRW) was 15.32/100 000,ranking the fifth of all cancers. The crude mortality rate(CMR) of liver cancer was 17.51/100 000(23.71/100 000 in male and 11.09/100 000 in female). The age-standardized mortality rate by world standard population(ASMRW) was 15.05/100 000,which was the fourth leading case of cancer death. The mortality rates displayed an increasing trend in Hebei Province during last 40 years as a whole,with an increased rate of 15.95%. In Ci County,the trends of incidence and mortality for both genders were similar.

Conclusion  The incidence and mortality rates of liver cancer in Hebei Province are much higher than the average level in the world. There is still a heavy health burden for liver cancer in Hebei Province. Thus,it is necessary to go on with taking measures to prevent and control liver cancer in the future.