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LI Yun-cheng, WANG Qun-xing, TAN Guang-xi, XIANG Xi-ying, LU Ji, ZENG Zhi-hua, LI Li-ya, ZHANG Xiao-lin, SONG Hao. MSCT Feature of Tumor Blood Supply Type in Patients with Hepatocellular Carcinoma :Correlation with Serum Vascular Endothel ial Growth Factor( VEGF)[J]. Cancer Research on Prevention and Treatment, 2007, 34(06): 446-448. DOI: 10.3971/j.issn.1000-8578.1397
Citation: LI Yun-cheng, WANG Qun-xing, TAN Guang-xi, XIANG Xi-ying, LU Ji, ZENG Zhi-hua, LI Li-ya, ZHANG Xiao-lin, SONG Hao. MSCT Feature of Tumor Blood Supply Type in Patients with Hepatocellular Carcinoma :Correlation with Serum Vascular Endothel ial Growth Factor( VEGF)[J]. Cancer Research on Prevention and Treatment, 2007, 34(06): 446-448. DOI: 10.3971/j.issn.1000-8578.1397

MSCT Feature of Tumor Blood Supply Type in Patients with Hepatocellular Carcinoma :Correlation with Serum Vascular Endothel ial Growth Factor( VEGF)

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  • Corresponding author:

    TAN Guang-xi

  • Received Date: January 31, 2007
  • Revised Date: April 05, 2007
  • Objective  To study the correlation between the multislice helical CT(MSCT) feature of tumor blood supply type in patients with hepatocellular carcinoma ( HCC) and the serum level of vascular endothelial growth factor (VEGF) . Methods  According to the cont rast-enhanced characteristic of lesion on MSCT, the tumor blood supply in 60 patients with HCC were classified into different types such as arterial blood supply, portal blood supply, arteroportal blood supply, and poorly blood supply. Enzyme linked immunosorbent assay ( ELISA) was used to test the serum levels of VEGF collected from 20 healthy individuals and 60 patient s with HCC respectively. At last, the CT features of tumor blood supply type were performed statistical analysis with the serum levels of VEGF. Results  The serum levels of VEGF in 20 patients with arterial blood supply type and 20 patients with arteroportal blood supply were significantly higher than that in 20 healthy individuals and 20 patients with portal blood supply or poorly blood supply type ( P < 0. 01) . There was no statistical significance of serum VEGF levels between 20 patients with portal blood supply or poorly blood supply type and 20 healthy individuals ( P > 0. 05) . Conclusion  The pattern of tumor blood supply for HCC on MSCT is correlative with the serum level of VEGF, and it is of great value in the interventional therapy for HCC.
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