Abstract: According to traditional principles of cancer surgery, tumor growth is undirected perifocal,irrespective of tissue barriers. However, some researches proposed a fresh insight at the anatomy based on embryology. Based on this concept, the current standard practice of local cancer surgery has been developed: total mesometrial resection(TMMR) without adjuvant radiation. This novel concept of embryologically based en bloc resection of a malignant solid tumor along the borders of the morphogenetic unit of its origin will definitely be highly innovative in the surgical treatment of early stage cervical cancer.