| [1] |
Warburg O.On the origin of cancer cells[J].Science,1956, 12 3(3191): 309-14.
|
| [2] |
Ma Y, Liang D, Liu J, et al. Prostate cancer cell lines under hypoxia exhibit greater stem-like properties[J]. PLoS One,2011,6(12): e29170.
|
| [3] |
Liang D, Ma Y, Liu J,et al. The hypoxic microenvironment upgrades stem-like properties of ovarian cancer cells[J]. BMC Cancer,2012, 12 :201.
|
| [4] |
Liu J, Fan H, Ma Y, et al. Notch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomas[J]. PLoS One,2013, 8(2): e56141.
|
| [5] |
Ciszak E, Korotchkina LG, Hong YS, et al. Crystallization and initial X-ray diffraction analysis of human pyruvate dehydrogenase[J]. Acta Crystallogr D Biol Crystallogr,2001, 57 (Pt 3): 465-8.
|
| [6] |
Koike K, Ohta S, Urata Y, et al. Cloning and sequencing of cDNAs encoding alpha and beta subunits of human pyruvate dehydrogenase[J]. Proc Natl Acad Sci U S A,1988,85(1):41-5.
|
| [7] |
Jeong JY, Jeoung NH, Park KG, et al. Transcriptional regulation of pyruvate dehydrogenase kinase[J]. Diabetes Metab J,2012,36(5):328-35.
|
| [8] |
Patel KP, O'Brien TW, Subramony SH, et al. The spectrum of pyruvate dehydrogenase complex deficiency: clinical, biochemical and genetic features in 371 patients[J]. Mol Genet Metab,2012,105(1):34-43.
|
| [9] |
Brown RM, Head RA, Boubriak II, et al. Mutations in the gene for the E1beta subunit: a novel cause of pyruvate dehydrogenase deficiency[J]. Hum Genet, 2004, 115(2):123-7.
|
| [10] |
Wu W, Zhao S. Metabolic changes in cancer: beyond the Warburg effect[J]. Acta Biochim Biophys Sin(Shanghai),2013, 45(1):18-26.
|
| [11] |
Lu CW, Lin SC, Chen KF, et al. Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance[J]. J Biol Chem,2008, 283(42):28106-14.
|
| [12] |
Lu CW, Lin SC, Chien CW, et al. Overexpression of pyruvate dehydrogenase kinase-3 increases drug resistance and early recurrence in colon cancer[J]. Am J Pathol,2011,179(3):1405-14.
|
| [13] |
Hur H, Xuan Y, Kim YB, et al. Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target[J]. Int J Oncol,2013,42(1):44-54.
|
| [14] |
McFate T, Mohyeldin A, Lu H, et al. Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells[J]. J Biol Chem,2008,283(33):22700-8.
|
| [15] |
Schwab LP, Peacock DL, Majumdar D, et al. Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer[J]. Breast Cancer Res,2012,14(1):R6.
|
| [16] |
Lee JH, Shim JW, Choi YJ, et al. The combination of sorafenib and radiation preferentially inhibits breast cancer stem cells by suppressing HIF-1α expression[J]. Oncol Rep,2013,29(3):917-24.
|
| [17] |
Zhao Y, Butler EB, Tan M. Targeting cellular metabolism to improve cancer therapeutics[J]. Cell Death Dis,2013, 4:e532.
|
| [18] |
Stacpoole PW. The pyruvate dehydrogenase complex as a therapeutic target for age-related diseases[J]. Aging Cell,2012,11(3):371-7.
|
| [19] |
Prasad C, Rupar T, Prasad AN, et al. Pyruvate dehydrogenase deficiency and epilepsy[J]. Brain Dev, 2011,33(10):856-65.
|
| [20] |
Barnerias C, Saudubray JM, Touati G, et al. Pyruvate dehydrogenase complex deficiency: four neurological phenotypes with differing pathogenesis[J]. Dev Med Child Neurol, 20 10,52(2):e1-9.
|
| [21] |
Roche TE, Hiromasa Y. Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia and cancer[J]. Cell Mol Life Sci, 2007, 64(7-8):830-49.
|
| [22] |
Kaplon J, Zheng L, Meissl K, et al. A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence[J]. Nature, 2013, 498(7452):109-12.
|
| [23] |
Blouin JM, Penot G, Collinet M, et al. Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex[J]. Int J Cancer, 2011, 128(11):2591-601.
|
| [24] |
Ferriero R, Brunetti-Pierri N. Anti-cancer drug phenylbutyrate increases activity of pyruvate dehydrogenase complex[J]. Oncotarget, 2013, 6(4):804-5.
|
| [25] |
Bonnet S, Archer SL, Allalunis-Turner J, et al. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth[J]. Cancer Cell,2007,11(1):37-51.
|
| [26] |
Cao W, Yacoub S, Shiverick KT, et al. Dichloroacetate (DCA) sensitizes both wild-type and over expressing Bcl-2 prostate cancer cells in vitro to radiation[J]. Prostate,2008,68(11):1223-31.
|
| [27] |
Fiebiger W, Olszewski U, Ulsperger E, et al. In vitro cytotoxicity of novel platinum-based drugs and dichloroac-etate against lung carcinoid cell lines[J]. Clin Transl Oncol, 2011, 13(1): 43-9.
|
| [28] |
Xie GF, Liang HJ, Tong JT, et al. Promoting effect of RNAinterfered pyruvate dehydrogenase kinase isozyme-1 on 5- fluorouracial-induced apoptosis of colon cancer cells[J]. J Third Mil Med Univ, 2012,34(1):9-12.
|
| [29] |
Chung S, Arrell DK, Faustino RS, et al. Glycolytic network restructuring integral to the energetics of embryonic stem cell cardiac differentiation[J]. J Mol Cell Cardiol,2010,48(4):725-34.
|
| [30] |
Varum S, Rodrigues AS, Moura MB, et al. Energy metabolism in human pluripotent stem cells and their differentiated counterparts[J]. PLoS One,2011,6(6):e20914.
|
| [31] |
Srinivasan M, Choi CS, Ghoshal P, et al. β-Cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion[J]. Am J Physiol Endocrinol Metab,2010,299(6):e910-7.
|
| [32] |
Sidhu S, Gangasani A, Korotchkina LG, et al. Tissue-specific pyruvate dehydrogenase complex deficiency causes cardiac hypertrophy and sudden death of weaned male mice[J]. Am J Physiol Heart Circ Physiol,2008,295(3): H946-52.
|
下载:
