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参脉注射液在食管癌放疗增敏中的作用

李东辉, 宁亚莉, 王海鹏, 余 敏, 李 晶, 姚淑莲

李东辉, 宁亚莉, 王海鹏, 余 敏, 李 晶, 姚淑莲. 参脉注射液在食管癌放疗增敏中的作用[J]. 肿瘤防治研究, 2014, 41(06): 598-601. DOI: 10.3971/j.issn.1000-8578.2014.06.019
引用本文: 李东辉, 宁亚莉, 王海鹏, 余 敏, 李 晶, 姚淑莲. 参脉注射液在食管癌放疗增敏中的作用[J]. 肿瘤防治研究, 2014, 41(06): 598-601. DOI: 10.3971/j.issn.1000-8578.2014.06.019
LI Donghui, NING Yali, WANG Haipeng, YU Min, LI Jing, YAO Shulian. Effects of Shenmai Injection Combined with Radiation on Esophageal Cancer[J]. Cancer Research on Prevention and Treatment, 2014, 41(06): 598-601. DOI: 10.3971/j.issn.1000-8578.2014.06.019
Citation: LI Donghui, NING Yali, WANG Haipeng, YU Min, LI Jing, YAO Shulian. Effects of Shenmai Injection Combined with Radiation on Esophageal Cancer[J]. Cancer Research on Prevention and Treatment, 2014, 41(06): 598-601. DOI: 10.3971/j.issn.1000-8578.2014.06.019

参脉注射液在食管癌放疗增敏中的作用

详细信息
    作者简介:

    李东辉(1969-),女,硕士,副主任医师,主要从事老年肿瘤内科治疗

  • 中图分类号: R735.1

Effects of Shenmai Injection Combined with Radiation on Esophageal Cancer

  • 摘要: 目的 观察参脉注射液在食管癌放疗过程中的增敏作用。方法 60例食管癌患者随机分两组单纯放疗组(对照组)、放疗+参脉组(治疗组),治疗组放疗同时应用参脉注射液60 ml+5%葡萄糖注射液250 ml,静滴,每日一次,连续使用4周。结果 在放疗剂量达60 Gy时,治疗组有效率为96%,单纯放疗组为73.3%,两者比较,差异有统计学意义(P=0.026);两组的安全性、肿瘤抑制率及生活质量比较差异均无统计学意义。结论 在食管癌放射治疗过程中应用参麦注射液,可以起到放疗增敏,提高疗效的作用。

     

    Abstract: Objective To investigate the effect of Shenmai injection on radiosensitivity in esophageal cancer patients. Methods Sixty patients diagnosed as esophageal cancer were randomized into two groups, treatment group with radiotherapy plus Shenmai injection, and control group with radiotherapy only. Two groups were given the same radioactive dosages. Treatment group was treated with radiotherapy and Shenmai injection 60 ml + 5% glucose injection 250 ml, intravenously(iv), quaque die(qd), for 4 weeks. Results The effective rate in treatment group was signifi cantly higher than that in control group (96% vs. 73.3%) (60 Gy, P<0.05). The reliability safety, quality of life and tumor inhibitory rates in treatment group were higher than those in control group, without signifi cant difference (P>0.05). Conclusion Radiotherapy combined with Shenmai injection for esophageal cancer could improve quality of life, increase radiosensitivity and curative effects.

     

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出版历程
  • 收稿日期:  2013-05-12
  • 修回日期:  2013-10-15
  • 刊出日期:  2014-06-24

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