Diagnostic Analysis of Liquid-base Cytology of 268 Cases of Endometrium
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摘要: 目的 探讨液基细胞学在子宫内膜病变中的诊断价值。方法 回顾性分析顺德区龙江医院和顺德区均安医院2010年12月—2012年12月行子宫内膜液基细胞学检查的病例268例，对照分段诊断性刮宫或全宫切除术后病理诊断进行对比分析。结果 268例液基细胞学标本的满意率96.64% （259/268），其中液基细胞学和组织学均满意的标本241例。液基细胞学诊断为未见上皮内病变、良性增生性改变、非典型增生、子宫内膜癌与组织学诊断结果符合率分别为86.84%(99/114) 、85.23%(75/88)、76.92%(20/26)、84.62%(11/13)。结论 子宫内膜液基细胞学标本的满意率高，其结果与组织病理诊断结果的符合率亦高，是子宫内膜病变有价值的诊断方法。非典型性增生是子宫内膜液基细胞学诊断的难点。Abstract: Objective To evaluate the diagnostic value of liquid-based cytology in the pathological changes of endometrium. Methods Two hundred and sixty-eight cases of pathological changes of endometrium detected by liquid-based cytology in Longjiang and JunAn hospitals of ShunDe district from December, 2010 to December, 2012 were retrospectively analyzed. Pathologic diagnosis of liquid-based cytology, fractional diagnostic curettage or total hysterectomy was contrastively analyzed. Results The sampling satisfaction rate of liquid-based cytology of the 268 samples was 96.64% (259/268), among which, there was 241 cases of both liquid-based cytology and histology satisfi ed samples, Liquid-based cytology diagnosis showed that coincidence rates of no intraepithelial pathological changes, innocence hyperplasia pathological changes, atypical hyperplasia and endometrial cancer with histodiagnosis result were 86.84%(99/114), 85.23%(75/88), 76.92%(20/26), 84.62%(11/13) respectively. Conclusion Both the sampling satisfaction rate of endometrial liquid-based cytology and the coincidence rate of its consequence and histology pathologic diagnosis were very high. Thus the endometrial liquid-based cytology was a valuable diagnostic method for pathological changes of endometrium. Atypical hyperplasia was the diffi culty of endometrial liquid-based cytology.
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