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老年肺癌住院死亡患者肺部感染影响因素分析

芮萌, 段蕴铀

芮萌, 段蕴铀. 老年肺癌住院死亡患者肺部感染影响因素分析[J]. 肿瘤防治研究, 2015, 42(03): 252-255. DOI: 10.3971/j.issn.1000-8578.2015.03.009
引用本文: 芮萌, 段蕴铀. 老年肺癌住院死亡患者肺部感染影响因素分析[J]. 肿瘤防治研究, 2015, 42(03): 252-255. DOI: 10.3971/j.issn.1000-8578.2015.03.009
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RUI Meng, DUAN Yunyou. Influencing Factors for Pulmonary Infection in Dead Elderly Inpatients with Lung Cancer[J]. Cancer Research on Prevention and Treatment, 2015, 42(03): 252-255. DOI: 10.3971/j.issn.1000-8578.2015.03.009
Citation: RUI Meng, DUAN Yunyou. Influencing Factors for Pulmonary Infection in Dead Elderly Inpatients with Lung Cancer[J]. Cancer Research on Prevention and Treatment, 2015, 42(03): 252-255. DOI: 10.3971/j.issn.1000-8578.2015.03.009
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老年肺癌住院死亡患者肺部感染影响因素分析

  • 100048 北京，海军总医院干部病房呼吸科

详细信息
    作者简介:

    芮萌（1969-），女，博士，副主任医师，主要从事肺癌的基础与临床研究

  • 中图分类号: R734. 2

Influencing Factors for Pulmonary Infection in Dead Elderly Inpatients with Lung Cancer

  • Respiratory Department of Cadre Wards, Naval General Hospital, Beijing 100048, China

摘要

    摘要
  • 摘要: 目的 探讨晚期老年肺癌住院患者死亡原因及肺部感染影响因素。方法 回顾性分析88例晚期老年肺癌住院患者死亡病例临床资料。结果 本组肺癌患者均≥65岁，功能状态评分>2分者占81.82%，90%以上至少有一处转移，基础病多，住院期间侵入性操作多，肺部感染是最主要的并发症，预后差，占死亡原因68.18%。病原菌以革兰氏阴性菌为主，常伴有真菌感染。3种以上抗肿瘤治疗、胸腔积液、肺部转移、住院时间长是肺部感染的危险因素。结论 肺部感染是晚期老年肺癌患者主要并发症和死亡原因。尽早发现转移灶，有效处理肺部及胸膜转移，减少易感因素，根据痰培养结果及时控制感染，是提高晚期老年肺癌患者治疗效果的关键。

     

    Abstract: Objective To investigate the death reasons for elderly inpatients with advanced lung cancer and the influencing factors on pulmonary infection. Methods A retrospective analysis was performed on 88 dead elderly patients with primary lung cancer. Results All patients were more than 65 years old. Performance status score >2 accounted for 81.82%. More than 90% of them had at least one organ metastasis. Most of them had multiple basic diseases and underwent one or more invasive operation during hospitalization. Pulmonary infection was the main complication. The prognosis was poor. 68.18% of the patients directly or indirectly died of pulmonary infection. Gram-negative bacteria were the main pathogens in patients with advanced lung cancer accompanied with fungal infection. More than three kinds of antineoplastic therapy, pleural effusion, pulmonary metastasis and long hospital stay were risk factors for pulmonary infection. Conclusion The pulmonary infection has become the most common cause of death and major complication in elderly patients with advanced lung cancer. Early detection of metastatic sites, effective treatment of pulmonary and pleural metastasis, reducing the susceptible factors and timely control of infection according to sputum culture are the main measures to improve the therapeutic efficacy in elderly patients with advanced lung cancer.

     

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出版历程
  • 收稿日期:  2014-03-08
  • 修回日期:  2014-10-23
  • 刊出日期:  2015-03-24

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