Red Cell Superoxide Dismutase Serum Lipid Peroxides and Vitamin E Levels in Patients with Leukemia
-
Graphical Abstract
-
Abstract
This article deals with determing the activity of the red cell superoxide dismutase (RBC-Cu.Zn-SOD),serum lipid peroxides (LPO)and vitamin E(VE) in 44cases of leukemia.The results indicated that activity of the RBC-Cu.Zn-SOD and LPO levels were markedly increased (P0.01) in patients of leukemia. Whereas VE concentration was notably decreased(P0.01).Trend observations have been made on 15 cases of acute leukemia.They had remission after treatment and their levels of RBC-Cu.Zn-SOD, LPO and VE went up to basically normal.These changes suggested that there was the disturbance of equilibrium between production and elimination of oxygen free radical in patients with leukemia. It revealed that distubance of equilibrium is partially recovered from treatment.
-
-