ENDOCRINE THERAPY FOR ADVANCED BREAST CANCER

53 cases of advanced breast cancer were divided into three groups according to the treatment.There were routine endocrine therapy group (22 cases)，tamosif en group (15 cases) and a minoglutethimide group (16 caser).Estrogen receptors(ER1 and progesteron receptors (PgR) we:e detected in the tumours of all patients by fluoroh- istochemical method, The effective rates of three endocrine therapy groups in ER-post ive patients were 76.9%，77, 8%，81.8%espectively, There were no statistically significant differences among three groups (P>0,05).The effective rates in ER- aegative patients were 0-10%.There were statistically signifticant difference between the effective rates and the levels of estro gen receptors (P < 0,001.The higher the level of the recepror, the higher the effective rate