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Qiao Naian, Lu Huilan, Wang Qingwei, . A Clinical Trial of Cisplatin in Combination with Radiation Therapy in Advanced Cervical Cancer[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 140-141.
Citation: Qiao Naian, Lu Huilan, Wang Qingwei, . A Clinical Trial of Cisplatin in Combination with Radiation Therapy in Advanced Cervical Cancer[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 140-141.

A Clinical Trial of Cisplatin in Combination with Radiation Therapy in Advanced Cervical Cancer

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  • 23 patients with advanced cervical cancer histologically proven were evaluated for response after treatment.They were divided into two groups: 1)radiosensitizing group(cisplatin plus irradiation, 9 pat Tent s),2) control group(radiotherapy alone, 14 patients),cisplatin was administered by intraarterial infusion to enhance radiosensitivity. 21 times of treatment were performed in the radiosensitizing group. All patients received radical radiotherapy to the tumor. The result show that the response rate of prim ary tumor in racliosensitizing group w as higher than in control group at the half close or fall close of the treatment, the difference was statistically significant(P<0.05).SER of cisplatin to primary lesion to partial remission and complete remission was 1.35 and 1.15 Mild side effects such as nausea, vomitting were ohserved.
  • [1]
    Souhami L.Weekly cisplatin plus external beam radiotherapy and high dose ratebrachtherapy in partients with bcally advanced careci nomn of the cervix lnt J Radit Oncol Biol, phys, 1993, 27(4):871
    [2]
    Seldinger SL.Cather replacement of needle in percutaneous arteriog raphy new technique.Acta Radiol,1953,39:368
    [3]
    WHO.Handhook for reporting rasults of cancer treatment.World Health Organization,Geuvae,1976,7
    [4]
    Miller AB. Reporting results of cancer treatment.Cancer.1985,47:207
    [5]
    Reboul Franccois,et al.Radiation therapy with concomitant contineous infusion cisplatin for unresectable nonsmall cell lung carcinoma.Int J Radiat Oncol Biol Phys,1994,28(5):125
    [6]
    Yang LX, Douple E,Wang HJ.Irradiation eahauce cellular uptake of carboplatin. lnt J Kadiat Oncul Biol phys, 1995, 33: 641
    [7]
    Yang LX, Douple E, Wang HJ.lrraditioifi eahauced binding of carboplation to DNA. lnt J liadiat Oncnl Biol phys, 1995,68:609
    [8]
    清水敬生,他.放射线疗法后の再发子宫颈部扁平上皮癌こ对 ずゐ持壳动注化学疗法.产妇人科の实际,1990, 391:205

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