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Li Aimin, Luo Rongcheng, Zhang Junyi, . The Study on the Treatment of the Malignant Tumor of Digestive Tract with 131I一CL3 in Tratumoral Injection Alone or Combined with LAK/IL-2 Intravenous Injection[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 123-124.
Citation: Li Aimin, Luo Rongcheng, Zhang Junyi, . The Study on the Treatment of the Malignant Tumor of Digestive Tract with 131I一CL3 in Tratumoral Injection Alone or Combined with LAK/IL-2 Intravenous Injection[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 123-124.
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The Study on the Treatment of the Malignant Tumor of Digestive Tract with 131I一CL3 in Tratumoral Injection Alone or Combined with LAK/IL-2 Intravenous Injection

  • Biotherapy and Research Center, Onmlogy Department, Nan Fang Hospital, Guang Zhou 510515

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  • Purpose:To explore the affection of the LAK/IL-2 intavenous injection(LAK/IL-2 IV) to the therapeutic cfficay of the radioimmunothcrapy .Method:There were 72 patients with malignant tumor of digestive tract in this study, 21 patients recepting 131I-CL3 intratumoral injection alone(131I一CL3 IT)，33 patients recepting LAK/IL一2 IV alone, and 18 patient recepting 131I一IL3 IT conbined with LAK/IL一2IV. Result:The therapeutic efficay of 131I一CL3 IT alone or LAK/IL一2 IV alone. Conclusion:LAK/IL-2 IV can enhance the therapeutic efFicay of raclicoimmunotherapy.
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    Fraker P,J,Speck ,JC.Protein and cell membrane iodintions with a sparingly soluble chlomamido 1,3,4,6-tetrnchlom-3α,Cradiphenyh gly-coluril.Biochem Biophys Res Commun, 1978, 80:849
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    曹雪涛主编.自细胞介素2的基础与临床，北京:科学技术出版社.1990,122
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    JolinWG,Claudio Du, Carol N, et al. Improved Radioimmuno-therapeutic efficacy of an anticarcinoma monoclonal antibody(1311-CC49)when given in combination with γ-interferon. Cancer res.1993, 53(Feb 1): 600
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