Advanced Search
Ouyang Xuenong, Chen Zhangshu, Zeng Jinxiong, . Clinial Value of Detection of Urinary Retinal-Binding Protein And β2-Microglobulin in Cancer Patients[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 120-122.
Citation: Ouyang Xuenong, Chen Zhangshu, Zeng Jinxiong, . Clinial Value of Detection of Urinary Retinal-Binding Protein And β2-Microglobulin in Cancer Patients[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 120-122.
shu

Clinial Value of Detection of Urinary Retinal-Binding Protein And β2-Microglobulin in Cancer Patients

  • Department of Medical Oncology, Fuzhou General Hospital, Fuzhou 350025

More Information
    Graphical Abstract
    • Abstract
  • It has been suggested that urinary retinal-binding protein(RBP)and (β2-microglobulin (β2-MG) excretion are very useful marker of proximal tubular defunction.To evaluate the relationship between RBP and β2-M Gin urine and proximal tubular impairment.The RBP and β2-MG levels in urine from 208 cancer patients were determined with RIA and ELISA separately. The results showed that the levels of RBP and β2-MG are significantly higher than control group. The positive rate of RBP and R2一MG is 62.50%and 62.02%respectively(P>0.05).The content of RBP in urine is less affected by extrarenal factor, RBP is more stable in urine than β2-MG, also the method detecting RBP is simpler than those of β2-MG.So we recommend that RBP may be more useful marker in diagnoseing the proximal tubular impairment in cancer patients.We condude that urinary RBP concentration can reflect the degree of renal damage in cancer patients sensitively.
    • FullText(HTML)
    • References (5)
  • [1]
    董德长主编.内科疾病肾脏表现.北京:人民卫生出版社,1986:299
    [2]
    Coheu AI, Harberg,J,Citriu DL.Measuremeut of urinary 2-mi-croglobulin in the deteetion of cisplatiu ueplirotoxicity.Cencer Treat Rep,1981,65:1083.
    [3]
    张桂生，郑玉衡，傅秀兰，等.酶联免疫技术及其临床应用.上海:上海第二医科大学出版社1994: 278.
    [4]
    朱承漠.放射免疫分析在肿瘤诊断中的应用进展.中华核医学杂志。1996, 6(3):196
    [5]
    Beetham R,DawnaY A London J, et al.A Radioimmunoassay for retinal-binding pmtein in serum and urine. Clip Chem, 1985, 31(7):1363
    • Related Articles

  • Related Articles

    [1]FENG Yu, QIAN Rulin, CUI Dong, CHANG Chaoying, CHEN Maolin. Serum β2-MG, sCHE, and PSGL-1 Expression in Patients with Esophageal Cancer and Their Association with Postoperative Lung Infection After Mediastinoscopy[J]. Cancer Research on Prevention and Treatment, 2025, 52(1): 68-73. DOI: 10.3971/j.issn.1000-8578.2025.24.0544
    [2]HU Wei, ZHU Hengcheng, LI Haoyong, LIU Xiuheng, ZENG Yan. CD248 Expression in Clear Cell Renal Cell Carcinoma and Its Clinical Significance[J]. Cancer Research on Prevention and Treatment, 2020, 47(3): 194-197. DOI: 10.3971/j.issn.1000-8578.2020.19.0776
    [3]WU Zhenghua, ZHOU Aiyun, ZHANG Cheng, XIAO Fan. Comparison of Application Value of Contrast Enhanced Ultrasound and Acoustic Radiation Force Impulse Imaging in Differential Diagnosis of Benign and Malignant Renal Tumors[J]. Cancer Research on Prevention and Treatment, 2016, 43(12): 1063-1066. DOI: 10.3971/j.issn.1000-8578.2016.12.011
    [4]Kang Hongyu, Ren Liang, Zhang Yinpo, Xu Hua. Breviscapine Prevents and Treats Renal Injury of Cisplatin through Antioxidant in Mice[J]. Cancer Research on Prevention and Treatment, 2012, 39(02): 154-156. DOI: 10.3971/j.issn.1000-8578.2012.02.009
    [5]LV Xiao-yun, TENG Yu-lian, ZHAO Jian-xiong, CHENG Wei-dong, BAI De-cheng. Effects of Fuzheng Jiedu Granula on Nickel-induced DNA Damage in Rrats Renal Cells[J]. Cancer Research on Prevention and Treatment, 2011, 38(08): 878-880. DOI: 10.3971/j.issn.1000-8578.2011.08.007
    [6]LUO Hong-bo, LIU Xiu-heng, CHEN Zhimin, ZHANG De-Ling. Immunohistochemical Study of COX-2 and MMP-2 in Human Renal Cell Carcinoma[J]. Cancer Research on Prevention and Treatment, 2005, 32(06): 354-346. DOI: 10.3971/j.issn.1000-8578.2783
    [7]ZHU Yu, WU Yu-xuan, ZHANG Cong-yu, LIU Ding-yi, ZHOU Wen-long, RUI Wen-bin, SUN Fu-kang. 3D DCE MRA in the Diagnosis of Renal Neoplasm[J]. Cancer Research on Prevention and Treatment, 2004, 31(03): 151-153. DOI: 10.3971/j.issn.1000-8578.1084
    [8]ZHANG Xiao-qing, CHEN Jian, CAO Guang-wen, et al, . Influence on the Oncogenes Expression of Renal Cell Carinoma (RCC) Cells Transduced with Human TNFA Gene[J]. Cancer Research on Prevention and Treatment, 2001, 28(05): 348-350. DOI: 10.3971/j.issn.1000-8578.1359
    [9]CHEN Dao-guang, HUANG Xue-zhen. Study on the Relationship between Hepatitis Virus(HBV) and Liver Damage in Chemotherapy of Lymphoma[J]. Cancer Research on Prevention and Treatment, 1999, 26(4): 268-269.
    [10]Li Tong-Du, . The Determination of ER, PR and β2-microglobulin Expression of Bladder Cancer Tissue In The Diagnosis And Prognosis Estimation of Bladder Tumor[J]. Cancer Research on Prevention and Treatment, 1996, 23(5): 265-267.

Catalog

    Get Citation
    PDF
    XML
    Article views (1112) PDF downloads (468) Cited by()
    Turn off MathJax
    Article Contents
    Abstract
    References
    Related Articles

    Download Center

    Links

    Contact Us

    Address：116 Zhuodaoquan South Road,
    Hongshan District, Wuhan（430079）

    Tel：027－87670126

    Email：zlfzyjzz@vip.163.com

    This work is licensed under a Creative Commons Attribution 3.0 License.

    Email Alert RSS
    Total visits：12183097 Visits today：6139

    Copyright © Editorial Department of Cancer Prevention Research 鄂公网安备 42011102005013号 鄂ICP备2022015867号

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return