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Dong Yuelan, Li Lin, Chen Lixin. The Relatonship Between the Expression of P16 in Ovarian Cancer and Clinical Stages[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 109-110.
Citation: Dong Yuelan, Li Lin, Chen Lixin. The Relatonship Between the Expression of P16 in Ovarian Cancer and Clinical Stages[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 109-110.

The Relatonship Between the Expression of P16 in Ovarian Cancer and Clinical Stages

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  • Objective To study the clinical meaning of P16 expression in ovarian cancer. We detected the expression of P16 in 19 cases of ovarian cancer and 10 cases of normal ovarians by using S-P immunohis to-chemical method. The results showed that in the ovarian cancer group P16 positive rate was 63.2%,3 cases advanced ovarian cancer were negative expressions and 4 cases Ic were weak positive expressions; and in the norm al ovarians group, the positive expression rate was 80%and weak positive expression rate was 10%.On the basis of above study.the mutation and deletion of P16 were closely related to recurrence devopement clinical stage and pathological grading of ovarian turner.
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    李楠,P16基因与肿瘤.国外医学肿瘤学分册,1995 22(5):257-259.
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    杨红,等.抑癌基因P16在卵巢肿瘤组织中的表达.中华妇产科杂志,1996,31(11):686-687.
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