Research of TGFβI and TGFβI II Receptors in Pancreatic Cancer

Zhang Lihui; Huang Daifa; Xu Fongzhi

Cancer Research on Prevention and Treatment > 1999 > 26(2): 91-93.

Zhang Lihui, Huang Daifa, Xu Fongzhi. Research of TGFβI and TGFβI II Receptors in Pancreatic Cancer[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 91-93.

Citation:

Zhang Lihui, Huang Daifa, Xu Fongzhi. Research of TGFβI and TGFβI II Receptors in Pancreatic Cancer[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 91-93.

Citation:

Zhang Lihui, Huang Daifa, Xu Fongzhi. Research of TGFβI and TGFβI II Receptors in Pancreatic Cancer[J]. Cancer Research on Prevention and Treatment, 1999, 26(2): 91-93.

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Research of TGFβI and TGFβI II Receptors in Pancreatic Cancer

General Hospital of N0.83.WenHua Road, Sheng Yang 110015

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Abstract

Purpose By analysis of TGFβ I and TGFβ II receptors, the relationship of two receptors was investigated in pancreatic cancer. Methods Twelve nofmal pancreas and 35 patients with pancreatic cancer were collected and analyzed by the ABC immunohistochemistry. Less than P<0.05 was significantly considered. Results The positive rates of TGFβI and TGFβII receptors were 68.6%(24/35)and 60%(21/35) respectively, both 51.4%(18/35 );The expressive correlation betty een TGFβ I and TGFβ II receptor genes, phase in pancreatic cancer was found(P<0.01)，but TGFβ II receptor has relationshiop with differentiation(P<0.05). Conclusion The results suggest tha expression of two receptors has relationship with pancreatic cancer and there is singnificance in diagnosis of pancreatic cancer.
- TGFβ I receptor,
- TGFβ II recepror,
- Pancreatic cancer

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References

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[3]	Cress T M Mullerpillasch F, Lerch MM, et al.Expression in situlocalization of genes coding for extracellular matrix protein and extra cellular matrix degrading proteases in pancreatic cancer.lnt ,J.Cancer.1995. 62.407-413.
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