CLINICAL RESEARCH OF CHEMOTHERAPY AND/OR RADIOTHERAPY FOR 276 CASES OF NONIHODGKIN'S LYMPHOMAS

From 1983 to June 1987, 276 cases of non-Hodgkin's lymphomas (NHL) treated by chemotherapy (CT) and/or Radiotherapy (RT) in our hospital. The ratio of male to female was 3.1: 1. The low, intermediate and high grade malignant lymphoma were 4.7%, 47%, 42.8% respectively The primary location in lymph nodes were 202cases (73.2%), out of the lymph nodes were 26.8%. There were 34, 92, 71 and 79 cases in stage Ⅰ, Ⅱ, Ⅲ and Ⅳ respectively, stage Ⅲ to Ⅳ occupy 54,4%, There were 98 cases at B group. On treatment, only combined CT 97 cases, CT+RT 179 cases, the regime of CT were COPP (CTX. VCR. PCZ PDN) CHOP (CTX ADM VCR PDN) MOPP (HN2 VCR PCZ PDN). After treatment, the CR+PR rate were reached to 76.5% (CR 42.8% PR 33.7%) and the one year survival of the whole group was 152 cases (55.1%), two years 106 cases (38.4%), three years 54 cases (29.3%), four years 23 cases (17.8%) five years 10 cases (19.2%), Among of 276 cases, the prognosis of NHL were related to the type of pathology, the stage of clinic, the A or B groups, the rate of CR+PR etc.