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Lei Xun, et al, . A STUDY OF A "HIGH RISK" NASOPHARYNGEAL cANCER FAMILY FOR THE CHROMOSOME ABERRATIONS[J]. Cancer Research on Prevention and Treatment, 1991, 18(3): 157-159.
Citation: Lei Xun, et al, . A STUDY OF A "HIGH RISK" NASOPHARYNGEAL cANCER FAMILY FOR THE CHROMOSOME ABERRATIONS[J]. Cancer Research on Prevention and Treatment, 1991, 18(3): 157-159.
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A STUDY OF A "HIGH RISK" NASOPHARYNGEAL cANCER FAMILY FOR THE CHROMOSOME ABERRATIONS

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  • A "high risk" nasopharyngeal cancer family was studied for the chromosome aberrations by peripheral lymphocyte culture with TC 199 medium of low folic acid and G—banding technique. The average chromosome aberration rates (CAR) of the family and the control group were 11.1% and 5.06% respectively, there is a highly significant difference between them (P0.001). The CAR of spouse group was 4.6%, no statistical difference as compared with the control one (P0.25). The translocation (7; 14) (p22; q22) was observed twice in the non-affected member of the family. The data Obtained suggest. 1. some members in the family have an increased chromosome instablity, possibly predisposing to NPC; 2. more difference between CAR of the family and the control can be taken under this culture condition.
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  • 1 Krumdieck Ch, et al: Am J Med Genot.1983； 16:23.
    2 Mattei MG. et al:Hum Genet 1981； 59:166.
    3 区宝祥、曾毅主编:鼻咽癌病因和发病学的研究，第116页，人民卫生出版社.1985.
    4 Lynch HT, et al eds: Cnncer Genetics P129 Illinois; Charles C Thomas. 1976.
    5 Mulvihill JJ, et al eds; Genetics of I-Iuman Cancer P105一114 New York:Raven, 1977,
    6 Herger R, et al, Cytogenet Cell Genet 1985;.40 (1一4):490,
    7 杨新明等:遗传与疾病1987: A:220
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