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Li Ji Ye, et al, . RELATION OF DNA PLOIDY LEVEL TO ESTROGEN RECEPTOR IN THE BREAST CANCER[J]. Cancer Research on Prevention and Treatment, 1991, 18(3): 145-148.
Citation: Li Ji Ye, et al, . RELATION OF DNA PLOIDY LEVEL TO ESTROGEN RECEPTOR IN THE BREAST CANCER[J]. Cancer Research on Prevention and Treatment, 1991, 18(3): 145-148.
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RELATION OF DNA PLOIDY LEVEL TO ESTROGEN RECEPTOR IN THE BREAST CANCER

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  • Tumor samples from 61 patients with primary breast cancer were measured for DNA ploidy level and Estrogen Receptor (ER) by flow cytometry and Histochemical fluorescence. Relationship between DNA ploidy Level and ER status was analyzed. The results showed 35 (57.4%) of 61 breast cancer were aneuploidy and remainder were diploidy. 34 (55.7%) of 61 breast cancer were ER-positive, 27 negative. Diploidy tumors were more often ER-positive and high differentiated than aneuploidy tumors (P0.01and0.001, respectivery). An inverse relationship was also observed, when percentage of ER-positive cell was decreased, the incidence of aneu ptoidy tumors may increased (P0.001). We suggest that DNA ploidy can be used as a new prognostic marker for breast cancer. If this investigatiOn combied with ER analysis may improved the effect of endocrine therapy in patients with breast cancer.
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  • 1 Feicher GE. et al. Cancer 1988; 41:823,
    2 Fallenius AG, et al. Cancer 1988, 62:521.
    3 Scharff RW. et al. I-Iistological typing of breast tumors, International Histological Classification of tumors NO. 2.Geneva: WHO 1968.
    4 陆家齐等:肿瘤防治研究1984; 11 ;198.
    5 Seckinger D, et al. Arch Path Lab Med 1989, 119:619.
    6 Poulsen HS. et al. Cancer 1981, 48:1791,
    7 Hedley DW. et al. Cancer 1984, 44:5396,
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