ASSAY OF ANTI—TUMOUR DRUG SENSITIVITY OF HUMAN MEGAkARYOBLASTIG LEUkEMIC CELL LINE (HI—MEG) AND SIGNIFICANCP
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Graphical Abstract
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Abstract
The sensitivity of human megakaryoblastic leukemic cell line(HI-Meg)and human promylocytic leukemic cell line (HL-60) to six clinical anti-tumour drugs was studied with ~3H-TdR incorporation, colony forming assay and alive cell account. These cell tines appeared proper dose respons curves and high sensitivity to six drugs HI-Meg cell line may be a new cellular model for screening for anti-tumour drugs, especially for effective drugs against megakaryoblastic leukemie.
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