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JianLin Yin et al, . ASSAY OF ANTI—TUMOUR DRUG SENSITIVITY OF HUMAN MEGAkARYOBLASTIG LEUkEMIC CELL LINE (HI—MEG) AND SIGNIFICANCP[J]. Cancer Research on Prevention and Treatment, 1991, 18(3): 133-135.
Citation: JianLin Yin et al, . ASSAY OF ANTI—TUMOUR DRUG SENSITIVITY OF HUMAN MEGAkARYOBLASTIG LEUkEMIC CELL LINE (HI—MEG) AND SIGNIFICANCP[J]. Cancer Research on Prevention and Treatment, 1991, 18(3): 133-135.
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ASSAY OF ANTI—TUMOUR DRUG SENSITIVITY OF HUMAN MEGAkARYOBLASTIG LEUkEMIC CELL LINE (HI—MEG) AND SIGNIFICANCP

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  • The sensitivity of human megakaryoblastic leukemic cell line(HI-Meg)and human promylocytic leukemic cell line (HL-60) to six clinical anti-tumour drugs was studied with ~3H-TdR incorporation, colony forming assay and alive cell account. These cell tines appeared proper dose respons curves and high sensitivity to six drugs HI-Meg cell line may be a new cellular model for screening for anti-tumour drugs, especially for effective drugs against megakaryoblastic leukemie.
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  • 1 Taetle R et al. J Natl cancer Inst 1988;80:720
    2 殷建林等。中国药理学通报1989; 5 :184
    3 Alley MC et al, Cancer Res 1988; 48:589
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    5 万景华等.中华血液学杂志1989; 10:292
    6 Huang MJ et al. Blood 1984; 64:427
    7 Ruiz-Arguelles GJ et al. Br J Haematol 1987:62:467
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