CISPLATIN ETOPOSIDE AND PINGYANGMYCIN COMDINATION THERAPY FOR ESOPHAGEAL CARCINOMA

The article reported thirty—three cases of esophagus epidermoid carcinoma at the middle and advanced stages were treated by cisplatin (DDP), Etoposide (PV-16) and pingyangmycin (PYM). The results showed, two patieets achieved complete remission (CR), thirteen patients had partial remission(PR), Eleven patiects had minor remission (MR). was 45.4% and total response rates (CR+PR+MR) was 78.8%. Remission rate of high-dose DDP group (40.9%) was lower than that of low-dose DDP group (54.5%), while total responserates of high-dose DDP group (81.8%) was higher than that of low-dose DDP group (72.7%). The median remiss ion duration of all patienjs was seven months. main sideeffectsandtoxicity were nausea, vom ting, anorexia bone marrow depression, alopecia, chill and fever.