STUDIES ON GSTS LEVELS OF DIFFERENT GROUPS OF PEOPLE IN HIGH RISK AREA OF LIVER CANCER

In the present study, GSTs levels in serum of different groups of people in Qidong City, a high risk area of liver cancer, were determined by means of biotin-avidin enzyme-linked, immunoassay (BA-ELISA).The results showed that the GSTs level of normal subjects in Qidong city (0,66土0.54ng/ml) was higher than that in Beijing (0.36土0.27ng/mI) Members of high cancer families, HBVsAg carriers and patients having a low-level fluctuating pattern of serum AFp are the population with high risk of Iiver cancer. The GSTs levels of 3 groups were 1.25士1.46, 1.43士1.44, and2.81士1.78ng/ml, respectively. It was significantly higher than in the normal . The higher GSTs level in the patients having a low-level fluctuating pattern of serum. AFP, may be nelatine to lecancenous hepatic lesions GSTs level in 57 liver cancer patients were 3.08土3.35ng/ml.This is a simple and rapid assay and coued be prediction of liver a useful aid the detection of liver dammage and in the high risk area of liver cancer, especially in the high risk area of liver cancer.