PROGNOSTIC SIGNIFICANCE AND DIFFERENTIATION OF AgNOR IN FIBROGENIC NEOPLASM

The argyrophilic nucleolar organizer region (AgNOR) of 88 cases with fibrogenic neoplasmwere quantitatively investigated, which included 6 cases of fibroma, 45 fibromatoid hyperplasia and37 fibrosarcoma. The results showed that a significant difference was found in the mean of AgNORamong three lesions and their subgroup (P0. 05, P0.001), and the survival time of the cases with a high AgNOR mean (≥5) was significant shorter than those with a low AgNOR mean (5) in 34 cases with librosarcoma followed up five years (P0. 05), and the 5-year survival rateswas 20% and 52% respectively. Therefore, the authors concluded that AgNOR has certain practical value for differentiating fibrogenic neoplasm and predicting the patients' prognosis.