Pathological study on expression of estrogen and progesterone in thyroid carcinoma, adenoma and normal tissues
-
Graphical Abstract
-
Abstract
Abstract Paraffin-embedded section from 67 cases with thyroid carcinoma, 20 cases with thyroid adenoma and 33 cases of normal thyroid tissues were assayed by enzyme-linked histochemical technique for the expression of ER (estrogen receptor) and PgR (Progesterone receptor). Results showed that the expression of receptor in carcinoma was much higher than that of adenoma and normal tisses (P<0. 01). The positive rate of ER and PgR in papillary carcinoma was highest, followed by follicular carcinoma, undifferentiated carcinoma and orther kinds of thyroid cancer. The PgR positive rate of the patients under the age of 40 was higher than those over 40 (P<0. 05). The PgR positive rate of female was higher than of male (P<0. 05). The study suggested that the PgR expression maybe offered a new reference for the differentiation of the cancer and grognosis of patients.
-
-