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Ni Qinggui, . Inhibition of β-Carotene on mice with ehrlich asciles carcinoma[J]. Cancer Research on Prevention and Treatment, 1997, 24(6): 371-372.
Citation: Ni Qinggui, . Inhibition of β-Carotene on mice with ehrlich asciles carcinoma[J]. Cancer Research on Prevention and Treatment, 1997, 24(6): 371-372.
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Inhibition of β-Carotene on mice with ehrlich asciles carcinoma

  • Department of molecular pharmacology, naval neurobiology research centre, Nanjing 210099

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  • Life-prolonging effects of β-Carotene (β-C ) on ehrlich ascites carcinoma (EAC)-bearlng mice were determined in the study. The results showed the mice life was prolonged, thymus index and spleen index were increased with the administration of β-C 5mg and 7.5mg. kg-1) (P＜0.05 for both dose groups), PHA-induced lymphocytes proliferation was enhanced by all dose groups (β-C 2. 3mg, 5mg, 7. 5mg·kg-1) (P＜0.05 for low dose group and P＜ 0.01 for both of medium dose group and high dose group). It is suggested that β-C can inhibit EAC, and it may be associated with enhancement of β-C on tumor immunity.
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    • References (4)
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    Regina GZ, Amy FS, Neal EC. Giske U. et al. Does β-Carotene Explain why reduced cancer risk is associ-ated with vegetable and fruit intake? Cancer Research (supple), 1992, 52:2060～2066.
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    Mathews R. Micheline M. Lansen N. et al. Effects of carotenoid adminstration on bladder cancer preven-tion. Oncology. 1991. 48:177～179.
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