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Xiao WenHua, . Study of the Mutation of P53 Gene in PrimaryHepatocellular Carcinoma in Southwest China[J]. Cancer Research on Prevention and Treatment, 1997, 24(3): 146-148.
Citation: Xiao WenHua, . Study of the Mutation of P53 Gene in PrimaryHepatocellular Carcinoma in Southwest China[J]. Cancer Research on Prevention and Treatment, 1997, 24(3): 146-148.
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Study of the Mutation of P53 Gene in PrimaryHepatocellular Carcinoma in Southwest China

  • Lab. of Gastroenterology, First Affiliated Hospital, Third Military University, Chongqing 630038

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  • Mutation ofP53 gene at codon were detected with PCR-RELP in primary hepastocellular carcinoma from Southwest China.The mutation of PS' gene at codon 249 were observed in 8 cases with positive of HBV serumal marker.However，no mutations at codon cases.The result suggest-ed that mutation at codon plays an importment role in HCC and AFB, may asso-ciate with a part of hepatocelluar carcinoma in Southwest China.
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  • [1]
    王俊茹，刘为纹，王冰，等.胃癌及癌旁组织中psa基5Hsu IG,Metcalf RA and Sun T,et al.Mutaional hot 因的研究·第三军医大学学报·1993.
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