Detection of P⁵³ gene mutation in non-small cell lung cancer by PCR-SSCP analysis

The present report was to investigate into P⁵³ NSCLC.Point mutation in exon and were gene mutation in patients with examined by polymerise chain reaction and single-strand conformation polymorsphism analysis in tumor tissues and embryonic tissue of the lung.Somatic Ps' mutations were detected in tumors Ps' gene alteration and According to TNM Stages，here was no difference NSCLC staging，such as for stage examined stage B and for stage Q .No Ps' mutation was embryonic tissues of the lung.Ps' mutations were detected in of between.