The analysis of dose-response relationship in the chemotherapy of refractory and relapsed Hodgkin's disease
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Graphical Abstract
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Abstract
The role of autologous bone marrow transplantation(ABMT) in the treatment of Hodgkin's disease (HD) remains controversial.Dose-response relationship is the theoretical basis of ABMT.24 groups of conventional salvage chemotherapy(CSC) material of HD, which were published in 82-94, was analyzed in this article and dose-response relationship couldn't be found in it.But the outcome of CSC is disappointed, with only 23% CR response to MOPP and ABVD have a strong indication for ABMT.
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