BCG,BCG and IL-2 intravesical instillation in the prevention of postopcrative recurrence of bladder tumor

Railway Medical College in Xuzhou, Xuzhou 221009For the prevention of tumor recurrence,intravesical instillation of only 150mg BCGwas instituated postoperatively in 40 cases of bladder cancer and intravesical instillationof a combination of 20000 unites of IL-2 and 100mg of BCG in another 34.In the BCGgroup, 80% (32/40) have been free of tumor for a mean time of 30.9 months (follow upranging from 18 to 72 months) and in the combination of BCG and IL-2 group, 88.3%(30/34) have been free of tumor for a mean time of 29.4% months (follwo up rangingfrom 16 to 70 months).Comparing the results of two groups, it is striking (P<0.01).The results revealed that BCG or combination BCG and IL-2 intravesilal instillation inthe prevention of tumor recurrence, which effect were very definited.The later groupwhat is more dominant, it decreased the dose of BCG and the side-effect minor.