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Liu Yunchu, . Immunohistochemical Study of Transforming Growth Factor-β2 in Prostatic Cancer[J]. Cancer Research on Prevention and Treatment, 1998, 25(4): 276-278.
Citation: Liu Yunchu, . Immunohistochemical Study of Transforming Growth Factor-β2 in Prostatic Cancer[J]. Cancer Research on Prevention and Treatment, 1998, 25(4): 276-278.
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Immunohistochemical Study of Transforming Growth Factor-β2 in Prostatic Cancer

  • Department of Urology, lst Affiliated Hospital, Hubei Medical University, Wuhan 430060

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  • Prostate tissue samples from patients with prostatic carcinoma (PC) and patientswith benign prostatic hyperplasia(BPH) were examined for the expression of transforming growth Factor-β2 (TGF-β2) using an immunohistochemical technique.All PC andBPH stroma showed positive staining and similar staining type.However, the staining ofTGF-β2 in the malignant epithelium of PC was significantly stronger and more extensivecompared with BPH, the differences were highly significant (P<0.01).Normal prostatetissue serving as controls showed no staining for TGF-β2 in epithelium in four cases.Stroma positive staining was noted in all four cases but was less extensive than that of PCon BPH.The findings suggest that TGF-β2 may be biologically important in the genesisand development of PC and BPH.
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    • References (8)
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