Radiotherapy of Non-Hodgkins Lymphoma(NHL) of the nasal cavity

Purpose: This paper analysis retrospectively 30 patients with NHL of nasal cavityfrom Jun. 1975 to Mar. 1993. Materials and Metods: 16 patients were treated by radiotherapy alone, and 14 by combination of radiotherapy with chemotherapy. The radiation doses of 15 patients were less than 45Gy, and the other 15 patients' were morethan 45 Gy. Results: The overall 5-year survival rate was 70.8% (lesions confined tothe nasal cavity 85.7% and lesions extending beyond the casal cavity 50.0%). 5-year survival rate for the patients treated by radiotherapy alone was 57.1%, by combined-therapy 90.0%. However the 5-year survival rate for the patients recievedthe radiation doses less than 45 Gy was 64.3%, the radiation dose more than 45 Gy 80 %. Conclusion: The results show, the lymph nodes of neck for the patients with lesions confined to the nasal cavity needn't be irradiated, the patients with lesions extending beyond the nasal cavity or involving regional lymph nodes had better be treatedby combination of radiotherapy with chemotherapy.