The Growth Inhibition and the effects of ultrastructure of DMSO and RA on Human Ovarian Cancer Cell COC1

The first affiliated hospital of Hubei MedicalThe effects of DMSO and RA on cell growth and ultrastructure in the cell werestudied by using ovarian cancer cell COC1 as a model. The results showed that the proliferation of COC1 cells was significantly inhibited by DMSO or RA, DMSO or RA canchange the structural characteristic of COC1 cell from malignant state to differentiatedone. It suggest that DMSO and RA have the ability to induce differentiation of humanovarian cancer cell.