The Value of Abdominal Drip Chemotherapy before and after Operation of Advanced Gastric and Large lnterstine

Objective To study the effect of abdominal paracentesis drip chemotherapy (APDC)before and after operation of advanced gastric and large interstine carcinoma (AGLIC) on preventing relapse and hepatometastasis as well as the practicablity of this method Methods One hundred and twenty seven patients with AGLIC were selected,and randomly divided into APDC'S(n=74) and vein chemotherapy's groups(n=53).The drugs,dosages and using period of the 2 groups were similar.The former were directly given the APDC before and after operations and the later done the peripheral vein chemotherapies after operations. Results After operations,there were significant difference in the rate of both the 2-year“non-tumor” survival and relapse metastasis between the 2 groups after operations(P<0.05).No chemtherapy's comlications developed in both the 2 groups. Conclusion The APDC before and after operation has abvious effect on preventing relapse and metastasis during the 2 years after the AGLIC operations,can effectively improve the existence quality,and is simple,safe and practical.