Preliminary Study on Patients with Nasopharyngeal Carcinoma Treated by Radiotherapy Combined with Fudr and Cisplatin

Objective To compare the response and side effects of FUDR plus DDP With 5-FU plus DDP fallowed by radiotherapy to treat patients with locally advanced nasopharyngeal carcinoma. Methods 46 patients with neck metastasis nasopharyngeal carcinoma were randomized into two groups:FUDR group or 5-FU group.FUDR 1000mg or 5-FU 1000mg plus DDP 20mg iv on day 1～5 for patients before radiotherapy.3 days after chemotherapy all patients received the same radiotherapy. Results 4 weeks after treatment,the effective rates...