A Discussion on the Expression of nm23 and TGF β_1 in Human Non-Small Cell Lung Cancer and Its Clinical and Pathological Correlation
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Graphical Abstract
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Abstract
Objective To discuss the level of expression of nm23, a metastasis suppressing gene and TGFβ 1 gene in human non small cell lung cancer, as well as its clinical and pathological correlation. Methods We investigated, at the level of protein synthesis the expression of the metastasis suppressing gene nm23 and TGF β 1 gene in the tissues of 83 human NSCLC specimens, by means of immunohistochemistry. Results The expression level of nm23 and TGFβ 1is closely correlated to TNM staging degree of differentiation,...
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