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HU Yong-sheng, ZHANG Qing-lin, TIAN Zhi-gang, et al, . The Autocrineor ParacrineInterleukin-6/Interleukin-6 Receptor Loop In Gliomas[J]. Cancer Research on Prevention and Treatment, 2001, 28(06): 429-431. DOI: 10.3971/j.issn.1000-8578.949
Citation: HU Yong-sheng, ZHANG Qing-lin, TIAN Zhi-gang, et al, . The Autocrineor ParacrineInterleukin-6/Interleukin-6 Receptor Loop In Gliomas[J]. Cancer Research on Prevention and Treatment, 2001, 28(06): 429-431. DOI: 10.3971/j.issn.1000-8578.949
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The Autocrineor ParacrineInterleukin-6/Interleukin-6 Receptor Loop In Gliomas

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  • Objective To evaluate the significance of the autocrine of paracrine interleukin-6/interleukin-6 receptor loop in gliomas. Methods We detected IL-6 and IL-6R gene in adult cerebral tissue, cerebellar tissue, 2glioma cell lines and 52 human glioma tissue specimens with different malignant degree. A complementary DNA copy of total RNA was synthesized and amplified with specific primers using the reverse transcription polymerase chain reaction(RT-PCR)method. Results The experiments revealed that both C6 and ...
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