Effects on Sensitivity to Chemotherapy in the Raji Cell Transfected with Exogenous HCAP1 Gene

Objective To investigate the effects of exogenous HCAP1 gene product on the sensitivity to chemotherapy in B lymphocytic lymphoma/leukemia cell line Raji. Methods HCAP1 gene was transfected into Raji cells by medium with liposome, The Raji cells stably expressing exogenous HCAP1 gene, which were screened by G418, exposed to various concentration of DNR, VP16 and VCR for 24 hours, the cell viability was measured by trypan blue dye exclusion test. Results Following exposure to various concentrations of DNR( ...