Detection and Analysis of Common Fusion Genes Related to Leukemias and Lymphomas

Objective To detect common fusion genes in 75 cases of leukemias and lymphomas by both nested multiplex RT PCR and chromosome karyotype. Methods Bone marrow samples from 75 patients, including 41 acute myelogenous leukemia (AML), 8 chronic myelogenous leukemia (CML), 1 chronic lymphoblastic leukemia (CLL), 1 prolymphocytic leukemia (PLL), 6 myelodysplastic syndrome (MDS), 8 non Hodgkin s lymphoma (NHL), 4 multiple myeloma (MM), 5 acute lymphoblastic leukemia (ALL), and 1 eosinophilic leukemia, were anal...