The Expression and Significance of Notch-1 Gene in Human Gliomas

Objective To study the expression of Notch-1 in human gliomas and the correlation between the expression and the pathological grades of gliomas,to explore the role of Notch-1 in the tumorigenesis and progression of human gliomas,accordingly to provide some proof of theory for treatment of human gliomas. Methods The expression of Notch-1 mRNA was detected in 70 primary human gliomas and 12 normal cerebral tissuses by using RT-PCR semi-quantity method. Results The expression of Notch-1 mRNA have been detected i...