Inhibitory Effects of c-erbB-2 Antisense Oligodeoxynucleotides Transfection on the Human Ovarian Carcinoma SKOV_3 Cell Lines

Objective To investigate the proliferating inhibition and the mechanisms of c-erbB-2 antisense oligodeoxynucleotides(ASODN) transfection on the human ovarian carcinoma SKOV_ 3 cell lines. Methods There were 4 groups in our study, blank control group,normal control group,c-erbB-2 sense control group and c-erbB-2 antisense experimental group.In the different time after liposome-mediated transfection,the cell proliferation,apoptosis,protein expressing level were observed by MTT assay,flow cytometry,fluorescent ...