Expressions of Epstein-Barr Virus Latent Membrane Protein 1(LMP1) and survivin in Nasopharyngeal Carcinoma and their Clinical Significance
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Graphical Abstract
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Abstract
Objective To investigate the expression of EBV-LMP1 and Survivin in nasopharyngeal poor differentiated squamous cell carcinoma and the correlation to prognosis. Methods The expression of LMP1 and survivin were detected by the SP immunohistochemical method in 83 NPC patients,and analyzed the relationship of their expressions with clinical stage and result after radiotherapy in three years. Results LMP1 was no correlation of clinical stage(P> 0.05 ),but correlated with relapse after radiotherapy in three yea...
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