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JIANG Jian-wei, ZHANG Yuan. Mechanism of c-myc Antisense Oligodeoxynucleotide Mediated by Receptor on the Proliferative Inhibition of Bel-7402 Cells[J]. Cancer Research on Prevention and Treatment, 2006, 33(10): 729-732. DOI: 10.3971/j.issn.1000-8578.873
Citation: JIANG Jian-wei, ZHANG Yuan. Mechanism of c-myc Antisense Oligodeoxynucleotide Mediated by Receptor on the Proliferative Inhibition of Bel-7402 Cells[J]. Cancer Research on Prevention and Treatment, 2006, 33(10): 729-732. DOI: 10.3971/j.issn.1000-8578.873
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Mechanism of c-myc Antisense Oligodeoxynucleotide Mediated by Receptor on the Proliferative Inhibition of Bel-7402 Cells

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  • Objective To observe the mechanism of c-myc antisense oligodeoxynucleotide mediated by galactose receptor on the proliferative inhibition of hepatocarcinoma Bel-7402 cells. Methods c-myc ASODN mixed with Galactose(Gal)- polyethyleneimine(PEI) reagent forming Gal-PEI-ASODN complex,then incubated with Bel-7402 cells for 48h,using Propidium Iodide(PI) dying,AnnexinV-FITC and PI double staining,DNA gel electrophoresis to detected the proliferative inhibition mechanism of Gal-PEI-ASODN on Bel-7402 cells. Results C...
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