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LI Chuang, LI Yang-qiu, YIN Qing-song, CHEN Shao-hua, YANG Li-jian, HU Gang. Analysis of Thymic Output of TCRVβ Subfamily nave T Cells in Patients with B-ALL[J]. Cancer Research on Prevention and Treatment, 2006, 33(11): 788-790. DOI: 10.3971/j.issn.1000-8578.855
Citation: LI Chuang, LI Yang-qiu, YIN Qing-song, CHEN Shao-hua, YANG Li-jian, HU Gang. Analysis of Thymic Output of TCRVβ Subfamily nave T Cells in Patients with B-ALL[J]. Cancer Research on Prevention and Treatment, 2006, 33(11): 788-790. DOI: 10.3971/j.issn.1000-8578.855
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Analysis of Thymic Output of TCRVβ Subfamily nave T Cells in Patients with B-ALL

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    • Abstract
  • Objective In order to investigate the recent thymic output function of TCR Vβ subfamily nave T cells in patients with B cell-acute lymphoblastic leukemia (B-ALL) by detection of the frequencies of 23 subfamilies of TCR Vβ sjTRECs in peripheral blood T cells. Methods 23 subfamilies of Vβ-Dβ1 sjTRECs were amplified in genomic DNA of peripheral blood mononuclear cells (PBMC) from 10 cases with B-ALL by using semi-nest PCR.10 normal individuals served as controls. Results TCR Vβ subfamilies of sjTRECs were detec...
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