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XU Dan, LIU Qi fa, SUN Jing, WEI Yong qiang, ZHANG Yu, MENG Fan yi. Antithymocyte Globulin vs Anti-CD3 Monoclonal Antibody Therapy for Patients with Steroid-resistant Acute Graft-versus-host Disease[J]. Cancer Research on Prevention and Treatment, 2004, 31(06): 359-361. DOI: 10.3971/j.issn.1000-8578.849
Citation: XU Dan, LIU Qi fa, SUN Jing, WEI Yong qiang, ZHANG Yu, MENG Fan yi. Antithymocyte Globulin vs Anti-CD3 Monoclonal Antibody Therapy for Patients with Steroid-resistant Acute Graft-versus-host Disease[J]. Cancer Research on Prevention and Treatment, 2004, 31(06): 359-361. DOI: 10.3971/j.issn.1000-8578.849
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Antithymocyte Globulin vs Anti-CD3 Monoclonal Antibody Therapy for Patients with Steroid-resistant Acute Graft-versus-host Disease

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  • Objective To observe the therapeutic effect of antithymocyte globulin combined with high dose methylprednisolone (ATG group) vs anti CD3 monoclonal antibody (WuT3 group) combined with high dose methylprednisolone(MP) on steroid refractory acute graft versus host disease (aGVHD). Methods Eleven patients with grade Ⅲ or Ⅳ aGVHD after allo HSCT who failed to respond to high dose MP were treated with ATG 2.5mg/(kg·d) for 5 to 7daysor WuT3(5mg/d for 10to 14 days). All patients continued to rec...
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