Increasing anti-tumor effect of arsenic trioxide combining with cisplatin on the QGY-7701 human hepatocarcinoma cells line

Objective To study the anti-tumor effect of arsenic trioxide combining with cisplatin on the human hepatocarcinoma cells line QGY-7701,and explore its mechanism. Methods Using MTT assay, flow cytometry and telomerase activiy detecting method etc. Results It was found that arsenic trioxide combining with cisplatin obviously increased the inhibitatory rates,apoptosis rate and inhibiting temolerase activity of the human hepatocarcinoma cells line QGY-7701 than those of the corresponding individual drug g...